Cholecalciferol (Vitamin D3)
| Empirical Formula (Hill Notation): | C27H44O |
| CAS Number: | 67-97-0 |
| Molecular Weight: | 384.64 |
| Beilstein/REAXYS Number: | 2339331 |
| EC Number: | 200-673-2 |
| MDL number: | MFCD00078131 |
| PubChem Substance ID: | 329823242 |
| NACRES: | NA.24 |
| Кат. номер |
| PHR1237-500MG |
| PHR1237-500MG-PW |
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Cholecalciferol (vitamin D3) is a fat-soluble vitamin that manifests skeletal and extra-skeletal effects. The skeletal effects augment the bone health whereas the extra-skeletal effects concern the immune system, the cognition, the cardiovascular system, etc.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Cholecalciferol (Vitamin D3) may be used as a pharmaceutical reference standard for the determination of the analyte in food, feeds, serum samples and pharmaceutical formulations by various chromatography techniques.
Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with
ISO 17034 and
ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC0270 in the slot below. This is an example certificate only and may not be the lot that you receive.
| Quality Level | 300 |
| grade | certified reference material, pharmaceutical secondary standard |
| form | neat, solid |
| CofA | current certificate can be downloaded |
| application(s) | HPLC: suitable, gas chromatography (GC): suitable |
| mp | 83-86 °C (lit.) |
| Featured Industry | Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule) |
| format | neat |
| pharmacopeia traceability | traceable to BP 787, traceable to PhEur C2100000, traceable to USP 1131009 |
| SMILES string | CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C |
| InChI | 1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1 |
| InChI key | QYSXJUFSXHHAJI-YRZJJWOYSA-N |
| Gene Information | human ... VDR(7421) |
| Pictograms | GHS06,GHS08 |
| Signal Word | Danger |
| Hazard Statements | H300 + H310 + H330 - H372 |
| Precautionary Statements | P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |