Reference Materials

For more information please see:
BCR068

BCR is a registered trademark of European Commission

grade	certified reference material
Agency/Method	BCR^®
form	particles
Торговая марка	JRC
particle size	160-630 µm
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat

pictograms	GHS08
signalword	Danger
hcodes	H350 - H372
pcodes	P201 - P202 - P260 - P264 - P270 - P308 + P313
Target Organs	Lungs
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Quartz (particle size) BCR132-700G

For more information please see:
BCR132

BCR is a registered trademark of European Commission

grade	certified reference material
Agency/Method	BCR^®
form	particles
Торговая марка	JRC
particle size	1400-5000
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat

pictograms	GHS08
signalword	Danger
hcodes	H350 - H372
pcodes	P201 - P202 - P260 - P264 - P270 - P308 + P313
Target Organs	Lungs
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Quartz (particle size) BCR130-50G

For more information please see:
BCR130

BCR is a registered trademark of European Commission

grade	certified reference material
Agency/Method	BCR^®
form	particles
Торговая марка	JRC
particle size	50-220 µm
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat

WGK Germany	nwg
Flash Point F	Not applicable
Flash Point C	Not applicable

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Quartz (particle size) BCR066-10G

EC Number:	238-878-4
NACRES:	NA.24

For more information please see:
BCR066

BCR is a registered trademark of European Commission

grade	certified reference material
Agency/Method	BCR^®
form	particles
Торговая марка	JRC
particle size	0.35-3.50 µm
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat

pictograms	GHS08
signalword	Danger
hcodes	H350 - H372
pcodes	P201 - P202 - P260 - P264 - P270 - P308 + P313
Target Organs	Lungs
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Quartz (particle size) BCR070-10G

For more information please see:
BCR070

BCR is a registered trademark of European Commission

grade	certified reference material
Agency/Method	BCR^®
form	particles
Торговая марка	JRC
particle size	1.20-20.00 µm
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat

pictograms	GHS08
signalword	Danger
hcodes	H350 - H372
pcodes	P201 - P202 - P260 - P264 - P270 - P308 + P313
Target Organs	Lungs
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Quartz (particle size) BCR067-10G

For more information please see:
BCR067

BCR is a registered trademark of European Commission

grade	certified reference material
Agency/Method	BCR^®
form	particles
Торговая марка	JRC
particle size	2.40-32.00 µm
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat

pictograms	GHS08
signalword	Danger
hcodes	H350 - H372
pcodes	P201 - P202 - P260 - P264 - P270 - P308 + P313
Target Organs	Lungs
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Quebec Ministry of Environmental Phenol MIx 502073

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Quality Level	100
grade	certified reference material
CofA	current certificate can be downloaded
packaging	ampule of 1 mL
concentration	2000 μg/mL in methanol
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Environmental
format	multi-component solution
storage temp.	2-8°C

pictograms	GHS02,GHS06,GHS08,GHS09
signalword	Danger
hcodes	H225 - H301 + H311 + H331 - H370 - H411
pcodes	P210 - P273 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany	WGK 3
Flash Point F	49.5 °F - closed cup
Flash Point C	9.7 °C - closed cup

Quercetin is a flavanol with strong antioxidant property. Due to the ability to scavenge free radicals and bind transition metal ions, quercetin is commonly used as a nutritional supplement and physiochemical remedy for a large number of diseases.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

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Quercetin

Empirical Formula (Hill Notation):	C₁₅H₁₀O₇ · xH₂O
CAS Number:	849061-97-8
Molecular Weight:	302.24 (anhydrous basis)
EC Number:	204-187-1
MDL number:	MFCD03847906
PubChem Substance ID:	329823412
NACRES:	NA.24

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Quercetin may be used as a pharmaceutical reference standard for the analysis of the analyte in biological samples and pharmaceutical formulations by high performance liquid chromatography (HPLC) and spectrophotometric methods.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB7760 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 1 g
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to PhEur Y0001009, traceable to USP 1592409
SMILES string	[H]O[H].Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(O)c3
InChI	1S/C15H10O7.H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;/h1-5,16-19,21H;1H2
InChI key	OKXFBEYCJRMINR-UHFFFAOYSA-N

pictograms	GHS06
signalword	Danger
hcodes	H301
pcodes	P264 - P270 - P301 + P310 - P405 - P501
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 1

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Quetiapine Fumarate

Empirical Formula (Hill Notation):	C₂₁H₂₅N₃O₂S · 0.5C₄H₄O₄
CAS Number:	111974-72-2
Molecular Weight:	441.54
MDL number:	MFCD03423782
NACRES:	NA.24

Quetiapine hemifumarate is an atypical antipsychotic, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAC0140 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 1 g
Featured Industry	Pharmaceutical
pharmacopeia traceability	traceable to PhEur Y0006157, traceable to USP 1592704
SMILES string	OC(=O)\C=C\C(O)=O.OCCOCCN1CCN(CC1)C2=Nc3ccccc3Sc4ccccc24.OCCOCCN5CCN(CC5)C6=Nc7ccccc7Sc8ccccc68
InChI	1S/2C21H25N3O2S.C4H4O4/c225-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h21-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+
InChI key	ZTHJULTYCAQOIJ-WXXKFALUSA-N
Gene Information	human ... DRD2(1813), HTR2A(3356), HTR2C(3358)

pictograms	GHS07,GHS09
signalword	Warning
hcodes	H302 - H400
pcodes	P273 - P301 + P312 + P330
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Quinapril Hydrochloride

Empirical Formula (Hill Notation):	C₂₅H₃₀N₂O₅ · HCl
CAS Number:	82586-55-8
Molecular Weight:	474.98
MDL number:	MFCD00889215
NACRES:	NA.24

Quinapril is a short-acting angiotensin converting enzyme (ACE) inhibitor.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAB1234 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 1 g
Featured Industry	Pharmaceutical
format	neat
pharmacopeia traceability	traceable to BP 1193, traceable to PhEur Y0001491, traceable to USP 1593401
SMILES string	Cl.CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2Cc3ccccc3C[C@H]2C(O)=O
InChI	1S/C25H30N2O5.ClH/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30;/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30);1H/t17-,21-,22-;/m0./s1
InChI key	IBBLRJGOOANPTQ-JKVLGAQCSA-N
Gene Information	human ... ACE(1636)

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Quinic Acid is a plant metabolite and a chiral building block used in multistep chemical synthesis of natural compounds.

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Quinic Acid

Empirical Formula (Hill Notation):	C₇H₁₂O₆
CAS Number:	77-95-2
Molecular Weight:	192.17
Beilstein/REAXYS Number:	2212412
EC Number:	201-072-8
MDL number:	MFCD00003864
PubChem Substance ID:	329823398

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAA3016 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 1 g
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to USP 1594506
SMILES string	O[C@@H]1C[C@@](O)(C[C@@H](O)[C@H]1O)C(O)=O
InChI	1S/C7H12O6/c8-3-1-7(13,6(11)12)2-4(9)5(3)10/h3-5,8-10,13H,1-2H2,(H,11,12)/t3-,4-,5-,7+/m1/s1
InChI key	AAWZDTNXLSGCEK-WYWMIBKRSA-N

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.

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Quinine

Empirical Formula (Hill Notation):	C₂₀H₂₄N₂O₂
CAS Number:	130-95-0
Molecular Weight:	324.42
Beilstein/REAXYS Number:	91867
EC Number:	205-003-2
MDL number:	MFCD00198096
PubChem Substance ID:	329761562
NACRES:	NA.24

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Potassium channel blocker

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Caution

Store under argon.

TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC

Quality Level	300
grade	certified reference material, TraceCERT^®
form	neat
shelf life	limited shelf life, expiry date on the label
storage condition	under inert gas
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	173-175 °C (lit.)
Featured Industry	Food and Beverages
format	neat
SMILES string	COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1
InChI	1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1
InChI key	LOUPRKONTZGTKE-WZBLMQSHSA-N

pictograms	GHS07,GHS08
signalword	Danger
hcodes	H302 - H315 - H317 - H319 - H334 - H335
pcodes	P261 - P264 - P280 - P280 - P304 + P340 + P312 - P342 + P311
Target Organs	Respiratory system
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

Rabeprazole Sodium belongs to the group of antisecretory compounds and is a proton pump inhibitor. It is widely used to suppress the gastric acid secretion by blocking the acid pump (H+ /K+ ATPase) at the secretory surface of the gastric parietal cell.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

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Rabeprazole Sodium

Empirical Formula (Hill Notation):	C₁₈H₂₀N₃O₃S · Na
CAS Number:	117976-90-6
Molecular Weight:	381.42
NACRES:	NA.24

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Rabeprazole Sodium may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography technique and spectrophotometric technique.

Rabeprazole sodium is gastric proton pump inhibitor. It suppresses the production of acid in the stomach by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Rabeprazole sodium has been used clinically to treat acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevent gastroinetestinal bleeds associated with NSAID use.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAA3643 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 1 g
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to USP 1598019
SMILES string	[Na+].COCCCOc1ccnc(CS(=O)c2nc3ccccc3[n-]2)c1C
InChI	1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1
InChI key	KRCQSTCYZUOBHN-UHFFFAOYSA-N
Gene Information	human ... ATP4A(495), ATP4B(496)

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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rac-Naproxen PHR2530-100MG

Empirical Formula (Hill Notation):	C₁₄H₁₄O₃
Linear Formula:	CH₃OC₁₀H₆CH(CH₃)CO₂H
CAS Number:	23981-80-8
Molecular Weight:	230.26
MDL number:	MFCD00439456

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAC4572 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 100 mg
pharmacopeia traceability	traceable to PhEur Y0000399, traceable to USP 1457301, traceable to USP 1457436
InChI	1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)
InChI key	CMWTZPSULFXXJA-UHFFFAOYSA-N

pictograms	GHS06
signalword	Danger
hcodes	H301
pcodes	P301 + P310 + P330
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Racemethionine PHR2653-500MG

Empirical Formula (Hill Notation):	C₅H₁₁NO₂S
Linear Formula:	CH₃SCH₂CH₂CH(NH₂)COOH
CAS Number:	59-51-8
Molecular Weight:	149.21
Beilstein/REAXYS Number:	636185
MDL number:	MFCD00063096

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAC4610 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 500 mg
mp	280 °C (dec.) (lit.)
pharmacopeia traceability	traceable to PhEur M0950000, traceable to USP 1643292
SMILES string	CSCCC(N)C(O)=O
InChI	1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
InChI key	FFEARJCKVFRZRR-UHFFFAOYSA-N

WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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Raloxifene Hydrochloride

Empirical Formula (Hill Notation):	C₂₈H₂₇NO₄S · HCl
CAS Number:	82640-04-8
Molecular Weight:	510.04
MDL number:	MFCD01938233

Raloxifene is a selective estrogen receptor modulator (SERM); acts as an anti-estrogen in both breast and uterine tissue while being estrogenic in bone. May have efficacy against estrogen-sensitive cancers.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAB0031 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 500 mg
Featured Industry	Pharmaceutical
format	neat
pharmacopeia traceability	traceable to PhEur Y0001134, traceable to USP 1598201
SMILES string	Cl[H].Oc1ccc(cc1)-c2sc3cc(O)ccc3c2C(=O)c4ccc(OCCN5CCCCC5)cc4
InChI	1S/C28H27NO4S.ClH/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29;/h4-13,18,30-31H,1-3,14-17H2;1H
InChI key	BKXVVCILCIUCLG-UHFFFAOYSA-N
Gene Information	human ... ESR2(2100)

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

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Raloxifene Related Compound C

Empirical Formula (Hill Notation):	C₂₈H₂₇NO₅S
CAS Number:	195454-31-0
Molecular Weight:	489.58
NACRES:	NA.24

To see an example of a Certificate of Analysis for this material enter LRAB5322 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 40 mg
Featured Industry	Pharmaceutical
format	neat
pharmacopeia traceability	traceable to USP 1598234

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

A certified reference standard suitable as a starting material for preparation of calibrators and controls in GC/MS or LC/MS testing applications with pharmaceutical research, clinical toxicology, urine drug testing, or forensic analysis. Marketed and sold under the trade name Rozerem®, ramelteon is a newer sleep aid approved by the FDA for treatment of insomnia, particularly delayed sleep onset. The drugs mode of action is unique for a sleep drug in that it does not bind to GABA receptors like the nonbenzodiazepines zolpidem, zopiclone, and zaleplon.

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Ramelteon solution

Empirical Formula (Hill Notation):	C₁₆H₂₁NO₂
CAS Number:	196597-26-9
Molecular Weight:	259.34
EC Number:	200-835-2
MDL number:	MFCD08067736
PubChem Substance ID:	329823976

CERILLIANT is a registered trademark of Cerilliant Corporation
Rozerem is a registered trademark of Takeda Pharmaceutical Company Limited
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Cerilliant Corporation

grade	certified reference material
Quality Level	300,
feature	Snap-N-Spike^®/Snap-N-Shoot^®
packaging	ampule of 1 mL
Торговая марка	Cerilliant^®
concentration	1.0 mg/mL in acetonitrile
Featured Industry	Pharmaceutical (small molecule)
format	single component solution
storage temp.	20°C
SMILES string	CCC(NCC[C@H]1C(C(CCO2)=C2C=C3)=C3CC1)=O
InChI	1S/C16H21NO2/c1-2-15(18)17-9-7-12-4-3-11-5-6-14-13(16(11)12)8-10-19-14/h5-6,12H,2-4,7-10H2,1H3,(H,17,18)/t12-/m0/s1
InChI key	YLXDSYKOBKBWJQ-LBPRGKRZSA-N
Gene Information	human ... MTNR1A(4543), MTNR1B(4544)

pictograms	GHS02, GHS07
signalword	Danger
hcodes	H225-H302 + H312 + H332-H319
pcodes	P210-P261-P302 + P352 + P312-P304 + P340 + P312-P337 + P313-P403 + P235
RIDADR	UN 1648 3 / PGII
WGK Germany	2
Flash Point F	35.6 °F
Flash Point C	2 °C

Ramipril is an angiotensin-converting-enzyme (ACE) inhibitor, which acts on the renin angiotensin aldosterone system. It is widely used in reducing hypertension by the suppression of the effects of angiotensin II at its receptor, thereby blocking the renin-angiotensin system.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

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Ramipril

Empirical Formula (Hill Notation):	C₂₃H₃₂N₂O₅
CAS Number:	87333-19-5
Molecular Weight:	416.51
MDL number:	MFCD00865775
PubChem Substance ID:	329822606
NACRES:	NA.24

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Ramipril may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique and high-performance liquid chromatography technique.

Angiotensin converting enzyme (ACE) inhibitor.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAC3757 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 1 g
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to BP 751, traceable to PhEur R0145000, traceable to USP 1598303
SMILES string	O=C(N1[C@](CCC2)([H])[C@]2([H])C[C@H]1C(O)=O)[C@H](C)N[C@H](C(OCC)=O)CCC3=CC=CC=C3
InChI	1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1
InChI key	HDACQVRGBOVJII-JBDAPHQKSA-N
Gene Information	human ... ACE(1636)

pictograms	GHS08
signalword	Warning
hcodes	H361f
pcodes	P201 - P202 - P280 - P308 + P313 - P405 - P501
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

Ranitidine hydrochloride is a H2-receptor antagonist, widely used for the management of hypersecretory conditions and for the treatment of duodenal ulcer.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

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Ranitidine hydrochloride

Empirical Formula (Hill Notation):	C₁₃H₂₂N₄O₃S · HCl
CAS Number:	66357-59-3
Molecular Weight:	350.86
EC Number:	266-333-0
MDL number:	MFCD00069339
PubChem Substance ID:	329823056
NACRES:	NA.24

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Ranitidine hydrochloride may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using titrimetry and visible spectrophotometry techniques.

H2 histamine receptor antagonist; anti-ulcer agent.
H2 histamine receptor antagonist; anti-ulcer agent.

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAA5630 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
form	neat
CofA	current certificate can be downloaded
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to BP 471, traceable to PhEur R0150000, traceable to USP 1598405
SMILES string	Cl[H].CN\C(NCCSCc1ccc(CN(C)C)o1)=C\[N+]([O-])=O
InChI	1S/C13H22N4O3S.ClH/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;/h4-5,9,14-15H,6-8,10H2,1-3H3;1H/b13-9-;
InChI key	GGWBHVILAJZWKJ-CHHCPSLASA-N

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

Подробнее

PHR2175-100MG

Ranitidine Impurity D PHR2175-100MG

Empirical Formula (Hill Notation): C₁₂H₁₈N₃NaO₄S

CAS Number: 112251-56-6

Molecular Weight: 323.34

General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC3713 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
Параметры

grade certified reference material, pharmaceutical secondary standard

packaging pkg of 100 mg

Safety Information

WGK Germany WGK 3

Flash Point F Not applicable

Flash Point C Not applicable

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Ranitidine Impurity F PHR2177-100MG

Empirical Formula (Hill Notation):	C₈H₁₄ClNO₂
Molecular Weight:	191.66

pictograms	GHS07
signalword	Warning
hcodes	H315 - H319 - H335
pcodes	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Target Organs	Respiratory system
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Ranitidine Impurity K PHR2182-100MG

Empirical Formula (Hill Notation):	C₄H₈N₂O₂S
Linear Formula:	O₂NCH=C(SCH₃)NHCH₃
CAS Number:	61832-41-5
Molecular Weight:	148.18
MDL number:	MFCD00040994

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAC5342 in the documents slot below. This is an example certificate only and may not be the lot that you receive.

grade	certified reference material, pharmaceutical secondary standard
packaging	pkg of 100 mg
mp	112-118 °C (lit.)
SMILES string	CN\C(SC)=C/[N+]([O-])=O
InChI	1S/C4H8N2O2S/c1-5-4(9-2)3-6(7)8/h3,5H,1-2H3/b4-3+
InChI key	YQFHPXZGXNYYLD-ONEGZZNKSA-N

pictograms	GHS07
signalword	Warning
hcodes	H315 - H319 - H335
pcodes	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Target Organs	Respiratory system
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ranitidine Related Compound A is an impurity of ranitidine, an inhibitor of gastric acid secretion. Ranitidine is widely used for treating gastric and duodenal ulcers.

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Ranitidine Related Compound A

Empirical Formula (Hill Notation):	C₁₀H₁₈N₂OS · 0.5 C₄H₄O₄
CAS Number:	91224-69-0
Molecular Weight:	272.36
NACRES:	NA.24

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Ranitidine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using kinetic spectrophotometric technique and electrochemical method.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAC0714 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 100 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to USP 1598507
SMILES string	OC(=O)\C=C\C(O)=O.CN(C)Cc1ccc(CSCCN)o1

RIDADR	NONH for all modes of transport
Flash Point F	Not applicable
Flash Point C	Not applicable

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

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Ranitidine Related Compound B

Empirical Formula (Hill Notation):	C₂₂H₃₅N₅O₄S₂
CAS Number:	72126-78-4
Molecular Weight:	497.67
Beilstein/REAXYS Number:	5365805
MDL number:	MFCD01727377
PubChem Substance ID:	329823604
NACRES:	NA.24

To see an example of a Certificate of Analysis for this material enter LRAC1515 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 100 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to USP 1598609
SMILES string	CN(C)Cc1ccc(CSCCN\C(NCCSCc2ccc(CN(C)C)o2)=C\[N+]([O-])=O)o1
InChI	1S/C22H35N5O4S2/c1-25(2)13-18-5-7-20(30-18)16-32-11-9-23-22(15-27(28)29)24-10-12-33-17-21-8-6-19(31-21)14-26(3)4/h5-8,15,23-24H,9-14,16-17H2,1-4H3
InChI key	VTVSRHZKBPARSF-UHFFFAOYSA-N

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

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Ranitidine Related Compound C

Empirical Formula (Hill Notation):	C₁₃H₂₂N₄O₄S
CAS Number:	73851-70-4
Molecular Weight:	330.40
Beilstein/REAXYS Number:	8395257
MDL number:	MFCD08063699
PubChem Substance ID:	329823605
NACRES:	NA.24

To see an example of a Certificate of Analysis for this material enter LRAC1065 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 100 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to USP 1598700
SMILES string	CN\C(NCCS(=O)Cc1ccc(CN(C)C)o1)=C/[N+]([O-])=O
InChI	1S/C13H22N4O4S/c1-14-13(9-17(18)19)15-6-7-22(20)10-12-5-4-11(21-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9+
InChI key	SKHXRNHSZTXSLP-UKTHLTGXSA-N

pictograms	GHS07,GHS08
signalword	Danger
hcodes	H317 - H334 - H335
pcodes	P261 - P280 - P284 - P304 + P340 + P312 - P333 + P313 - P342 + P311
Target Organs	Respiratory system
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Ranolazine PHR2676-500MG

Empirical Formula (Hill Notation):	C₂₄H₃₃N₃O₄
CAS Number:	95635-55-5
Molecular Weight:	427.54

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAC6032 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 500 mg
pharmacopeia traceability	traceable to USP 1598744
InChI	1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)
InChI key	XKLMZUWKNUAPSZ-UHFFFAOYSA-N

WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Ranolazine Related Compound A PHR2677-100MG

Empirical Formula (Hill Notation):	C₁₀H₁₂O₃
CAS Number:	2210-74-4
Molecular Weight:	180.20

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAC6034 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

grade	certified reference material, pharmaceutical secondary standard
packaging	pkg of 100 mg
pharmacopeia traceability	traceable to USP 1598755
InChI	1S/C10H12O3/c1-11-9-4-2-3-5-10(9)13-7-8-6-12-8/h2-5,8H,6-7H2,1H3
InChI key	RJNVSQLNEALZLC-UHFFFAOYSA-N

pictograms	GHS07
signalword	Warning
hcodes	H315 - H317
pcodes	P261 - P264 - P272 - P280 - P302 + P352 - P333 + P313
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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PHR2678-100MG

Ranolazine Related Compound B PHR2678-100MG

Empirical Formula (Hill Notation): C₂₃H₃₁N₃O₃ · 2HCl · H₂O

Molecular Weight: 488.45

General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC6845 in the documents slot below. This is an example certificate only and may not be the lot that you receive.
Параметры

grade certified reference material, pharmaceutical secondary standard

packaging pkg of 100 mg

pharmacopeia traceability traceable to USP 1598766

storage temp. 2-30°C

Safety Information

WGK Germany WGK 3

Flash Point F Not applicable

Flash Point C Not applicable

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Ranolazine Related Compound C PHR2679-100MG

Empirical Formula (Hill Notation):	C₁₄H₂₁N₃O
CAS Number:	5294-61-1
Molecular Weight:	247.34

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAC6031 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

grade	certified reference material, pharmaceutical secondary standard
packaging	pkg of 100 mg
pharmacopeia traceability	traceable to USP 1598777
InChI	1S/C14H21N3O/c1-11-4-3-5-12(2)14(11)16-13(18)10-17-8-6-15-7-9-17/h3-5,15H,6-10H2,1-2H3,(H,16,18)/p+2
InChI key	NJKRFQIWDJSYOK-UHFFFAOYSA-P

pictograms	GHS05,GHS07
signalword	Danger
hcodes	H302 - H317 - H318
pcodes	P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

For more information please see:
ERMBC190

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PHR2680-100MG

Ranolazine Related Compound D PHR2680-100MG

Empirical Formula (Hill Notation): C₂₄H₃₂N₄O₂

CAS Number: 380204-72-8

Molecular Weight: 408.54

General description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Analysis Note
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Footnote
To see an example of a Certificate of Analysis for this material enter LRAC4994 in the documents slot below. This is an example certificate only and may not be the lot that you receive.
Параметры

grade certified reference material, pharmaceutical secondary standard

packaging pkg of 100 mg

pharmacopeia traceability traceable to USP 1598788

Safety Information

WGK Germany WGK 3

Flash Point F Not applicable

Flash Point C Not applicable

Узнать цену Получить предложение
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Rapeseed (S, total glucosinolate) ERMBC190-20G

Certified for the analytes listed below. See certificate for values and more details
Phytochemicals: Total glucosinolate (GSL)
Trace Elements: Sulphur

ERM is a registered trademark of European Commission

grade	certified reference material
Agency/Method	ERM^®, certified by the BSC
Торговая марка	JRC
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule)
format	matrix material
storage temp.	2-8°C

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Rapeseed (S, total glucosinolate) ERMBC367-20G

Rapeseed (S, total glucosinolate) has been used as a reference material in the determination of glucosinolates in horseradish plant extract using liquid chromatography coupled to high resolution mass spectrometry (LC-MS).

For more information please see:
ERMBC367

Certified for the analytes listed below. See certificate for values and more details
Phytochemicals: Total glucosinolate (GSL)
Trace Elements: Sulphur

ERM is a registered trademark of European Commission

grade	certified reference material
Agency/Method	ERM^®, certified by the BSC
Торговая марка	JRC
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule)
format	matrix material
storage temp.	2-8°C

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Rapeseed (S, total glucosinolate) ERMBC366-20G

For more information please see:
ERMBC366

Certified for the analytes listed below. See certificate for values and more details
Phytochemicals: Total glucosinolate (GSL)
Trace Elements: Sulphur

ERM is a registered trademark of European Commission

grade	certified reference material
Agency/Method	ERM^®, certified by the BSC
Торговая марка	JRC
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule)
format	matrix material
storage temp.	2-8°C

WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

Rare earth elements is a group of elements that expands from lanthanum to lutetium, which exhibit similar physical and chemical properties.It can be found in rocks and minerals.
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to SI unit kg and measured against primary material from an NMI, e.g. NIST.
Certified content incl. uncertainty and expiry date are given on the certificate.

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Rare earth element mix for ICP

50 mg/L each: Sc, Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb and Lu in 2% nitric acid

TraceCERT is a registered trademark of Sigma-Aldrich Co. LLC

Quality Level	300
grade	certified reference material, TraceCERT^®
product line	TraceCERT^®
shelf life	limited shelf life, expiry date on the label
concentration	50 mg/L in nitric acid
application(s)	ICP: suitable
format	multi-component solution

pictograms	GHS05
signalword	Warning
hcodes	H290 - H315 - H319
pcodes	P234 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
RIDADR	UN 3264 8 / PGIII
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

Подробнее

Rebaudioside A PHR2697-1G

Empirical Formula (Hill Notation):	C₄₄H₇₀O₂₃
CAS Number:	58543-16-1
Molecular Weight:	967.01
Beilstein/REAXYS Number:	6470556
MDL number:	MFCD02183463

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAC7556 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

grade	certified reference material, pharmaceutical secondary standard
packaging	pkg of 1 g, pkg of
storage temp.	2-8°C
SMILES string	C[C@@]12CCC[C@](C)([C@H]1CC[C@]34CC(=C)C(CC[C@@H]23)(C4)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@H]5O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C(=O)O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O
InChI	1S/C44H70O23/c1-17-11-43-9-5-22-41(2,7-4-8-42(22,3)40(59)66-38-33(58)30(55)26(51)20(14-47)62-38)23(43)6-10-44(17,16-43)67-39-35(65-37-32(57)29(54)25(50)19(13-46)61-37)34(27(52)21(15-48)63-39)64-36-31(56)28(53)24(49)18(12-45)60-36/h18-39,45-58H,1,4-16H2,2-3H3/t18-,19-,20-,21-,22+,23+,24-,25-,26-,27-,28+,29+,30+,31-,32-,33-,34+,35-,36+,37+,38+,39+,41-,42-,43-,44+/m1/s1
InChI key	HELXLJCILKEWJH-NCGAPWICSA-N

WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Reserpine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry and spectrofluorimetry.

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Reserpine

Empirical Formula (Hill Notation):	C₃₃H₄₀N₂O₉
CAS Number:	50-55-5
Molecular Weight:	608.68
Beilstein/REAXYS Number:	102014
EC Number:	200-047-9
MDL number:	MFCD00005091
PubChem Substance ID:	329823594
NACRES:	NA.24

Inhibits vesicular uptake of catecholamines and serotonin.

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAA7915 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 1 g
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	~265 °C (dec.)
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to PhEur R0200000, traceable to USP 1601000
SMILES string	CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6
InChI	1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
InChI key	QEVHRUUCFGRFIF-MDEJGZGSSA-N
Gene Information	human ... SLC18A2(6571)

pictograms	GHS07,GHS08
signalword	Danger
hcodes	H302 - H336 - H351 - H360D
pcodes	P201 - P301 + P312 + P330 - P308 + P313
Target Organs	Central nervous system
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent - Acetonitrile is a CRM and Secondary Pharmaceutical Reference Standard, traceable and qualified against the corresponding Pharmacopeial standards. Sigma-Aldrich offers Fluka brand Certified Reference Materials (CRMs) for the analysis of Residual Solvents. A comprehensive Certificate of Analysis offers details of the methodology and results of the qualification.

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Residual Solvent - Acetonitrile

Empirical Formula (Hill Notation):	C₂H₃N
Linear Formula:	CH₃CN
CAS Number:	75-05-8
Molecular Weight:	41.05
Beilstein/REAXYS Number:	741857
EC Number:	200-664-3
MDL number:	MFCD00001878
PubChem Substance ID:	329823305
NACRES:	NA.24

To see an example of a Certificate of Analysis for this material enter LRAA0679 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
vapor density	1.41 (vs air)
vapor pressure	72.8 mmHg ( 20 °C)
CofA	current certificate can be downloaded
autoignition temp.	973 °F
expl. lim.	16 %
application(s)	HPLC: suitable, gas chromatography (GC): suitable
refractive index	n20/D 1.344 (lit.)
bp	81-82 °C (lit.)
mp	45 °C (lit.)
density	0.786 g/mL at 25 °C (lit.)
Featured Industry	Pharmaceutical (small molecule)
format	single component solution
pharmacopeia traceability	traceable to USP 1601340
SMILES string	CC#N
InChI	1S/C2H3N/c1-2-3/h1H3
InChI key	WEVYAHXRMPXWCK-UHFFFAOYSA-N

RIDADR	NA 1993 / PGIII
WGK Germany	nwg
Flash Point F	188.6 °F - closed cup
Flash Point C	87 °C - closed cup

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent - Benzene is a certified reference material for the screening and quantification of residual solvents. This CRM is a secondary pharmaceutical reference standard and is traceable and qualified against the corresponding pharmacopeial standards.

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Residual Solvent - Benzene

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAA0677 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
Featured Industry	Pharmaceutical (small molecule)
format	single component solution
pharmacopeia traceability	traceable to USP 1601146

pictograms	GHS08
signalword	Danger
hcodes	H340 - H350
pcodes	P201 - P202 - P280 - P308 + P313 - P405 - P501
RIDADR	UN 1993 / PGIII
WGK Germany	WGK 3
Flash Point F	188.6 °F - closed cup
Flash Point C	87 °C - closed cup

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

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Residual Solvent - Chloroform

Empirical Formula (Hill Notation):	CHCl₃
CAS Number:	67-66-3
Molecular Weight:	119.38
Beilstein/REAXYS Number:	1731042
EC Number:	200-664-3
MDL number:	MFCD00000826
PubChem Substance ID:	329823302
NACRES:	NA.24

To see an example of a Certificate of Analysis for this material enter LRAA0675 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
vapor density	4.1 (vs air)
vapor pressure	160 mmHg ( 20 °C)
CofA	current certificate can be downloaded
application(s)	HPLC: suitable, gas chromatography (GC): suitable
refractive index	n20/D 1.445 (lit.)
bp	60.5-61.5 °C (lit.)
mp	63 °C (lit.)
density	1.492 g/mL at 25 °C (lit.)
Featured Industry	Pharmaceutical (small molecule)
pharmacopeia traceability	traceable to USP 1601383
SMILES string	ClC(Cl)Cl
InChI	1S/CHCl3/c2-1(3)4/h1H
InChI key	HEDRZPFGACZZDS-UHFFFAOYSA-N

WGK Germany	WGK 2
Flash Point F	185.0 °F - closed cup
Flash Point C	85 °C - closed cup

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent - Methanol is a CRM and a Secondary Pharmaceutical Reference Standard, traceable and qualified against the corresponding Pharmacopeial standards. Sigma-Aldrich offers Fluka brand Certified Reference Materials (CRMs) for the analysis of Residual Solvents. A comprehensive Certificate of Analysis offers details of the methodology and results of the qualification.

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Residual Solvent - Methanol

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Values of analytes vary lot to lot.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAA7144 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
suitability	suitable for 467 per USP
Featured Industry	Environmental Pharmaceutical (small molecule)
format	single component solution
pharmacopeia traceability	traceable to USP 1601623

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	188.6 °F - closed cup - Solvent
Flash Point C	87 °C - closed cup - Solvent

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent - Methylene Chloride belongs to the class of certified reference materials for the screening and quantification of residual solvents. These CRMs are secondary pharmaceutical reference standards and are traceable and qualified against the corresponding pharmacopeial standards. A comprehensive Certificate of Analysis offers details of the methodology and results of the qualification.

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Residual Solvent - Methylene Chloride

EC Number:	200-664-3
NACRES:	NA.24

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAA7143 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
suitability	suitable for 467 per USP
Featured Industry	Environmental Pharmaceutical (small molecule)
format	single component solution
pharmacopeia traceability	traceable to USP 1601441

RIDADR	UN 1993 / PGIII
WGK Germany	WGK 1
Flash Point F	188.6 °F - closed cup - Solvent
Flash Point C	87 °C - closed cup - Solvent

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent - Trichloroethylene belongs to the group of class 2 residual solvents. The use of class 2 solvents should be limited in drug substances, excipients, dietary ingredients, and official products because of the inherent toxicities of these residual solvents. Trichloroethylene is a volatile and chlorinated organic compound, which finds applications as a solvent and greasing agent.

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Residual Solvent - Trichloroethylene

Empirical Formula (Hill Notation):	C₂HCl₃
Linear Formula:	ClCH=CCl₂
CAS Number:	79-01-6
Molecular Weight:	131.39
Beilstein/REAXYS Number:	1736782
MDL number:	MFCD00000838
PubChem Substance ID:	329823304

To see an example of a Certificate of Analysis for this material enter LRAA0678 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
vapor density	4.5 (vs air)
vapor pressure	61 mmHg ( 20 °C)
CofA	current certificate can be downloaded
autoignition temp.	770 °F
application(s)	HPLC: suitable, gas chromatography (GC): suitable
refractive index	n20/D 1.476 (lit.)
bp	86.7 °C (lit.)
mp	84.8 °C (lit.)
density	1.463 g/mL at 25 °C (lit.)
Featured Industry	Pharmaceutical (small molecule)
format	single component solution
pharmacopeia traceability	traceable to USP 1601827
SMILES string	Cl\C=C(\Cl)Cl
InChI	1S/C2HCl3/c3-1-2(4)5/h1H
InChI key	XSTXAVWGXDQKEL-UHFFFAOYSA-N

pictograms	GHS08
signalword	Danger
hcodes	H350
pcodes	P201 - P202 - P280 - P308 + P313 - P405 - P501
RIDADR	NA 1993 / PGIII
WGK Germany	WGK 3
Flash Point F	188.6 °F - closed cup
Flash Point C	87 °C - closed cup

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvents Mixture - Class IIA are certified reference materials (CRMs) for the analysis of residual solvents. The residual solvents can be found as mixtures, as single-analyte standards, as well as neat CRMs. These CRMs are secondary pharmaceutical reference standards and are traceable and qualified against the corresponding Pharmacopeial standards.

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Residual Solvents Mixture - Class IIA

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

To see an example of a Certificate of Analysis for this material enter LRAB7797 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
suitability	suitable for 467 per USP
Featured Industry	Environmental Pharmaceutical (small molecule)
format	multi-component solution
pharmacopeia traceability	traceable to USP 1601281