Phentolamine Mesylate

Empirical Formula (Hill Notation):	C17H19N3O · CH4O3S
Linear Formula:	C17H19N3O · CH3SO3H
CAS Number:	65-28-1
Molecular Weight:	377.46
EC Number:	200-604-6
MDL number:	MFCD00134201
PubChem Substance ID:	329823376
NACRES:	NA.24

Кат. номер

PHR1403-1G

PHR1403-1G-PW

Phentolamine Mesylate belongs to the class of alpha adrenergic antagonist drugs. It is used in the treatment of pheochromocytoma-related hypertension, erectile dysfunction and in the diagnosis of pheochromocytoma and norepinephrine-related dermal necrosis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Phentolamine Mesylate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chemiluminescence technique.
α-Adrenergic receptor antagonist; peripheral vasodilator.
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC3261 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
form	neat
CofA	current certificate can be downloaded
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	180-182 °C (lit.)
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to PhEur Y0001127, traceable to USP 1530004
SMILES string	CS(O)(=O)=O.Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3
InChI	1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4)
InChI key	OGIYDFVHFQEFKQ-UHFFFAOYSA-N
Gene Information	human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

pictograms	GHS07
signalword	Warning
hcodes	H302 - H315 - H319 - H335
pcodes	P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
Target Organs	Respiratory system
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable