Oxytetracycline

Empirical Formula (Hill Notation):	C22H24N2O9 · 2H2O
CAS Number:	6153-64-6
Molecular Weight:	496.46
EC Number:	201-212-8
MDL number:	MFCD00151234
PubChem Substance ID:	329823449
NACRES:	NA.24

Кат. номер

PHR1537-1G

PHR1537-1G-PW

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Oxytetracycline is a broad-spectrum antibiotic which finds a wide use in veterinary medicine because of its potential to inhibit the protein synthesis in gram-positive and gram-negative bacteria. It can be used on animal species like cattle, sheep, goats and pigs.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Oxytetracycline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and spectrofluorimetry techniques.
Antibiotic produced by Streptomyces rimosus.
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation.
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC0364 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 1 g
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to BP 782, traceable to PhEur Y0001896, traceable to USP 1491004
SMILES string	O.[H][C@@]12[C@@H](O)[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C
InChI	1S/C22H24N2O9.H2O/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25,27-29,32-33H,1-3H3,(H2,23,31);1H2/t12-,13-,14+,17+,21-,22+;/m1./s1
InChI key	IBZHEBHGZFICKS-IFLJXUKPSA-N

pictograms	GHS08,GHS09
signalword	Warning
hcodes	H361d - H411
pcodes	P201 - P202 - P273 - P280 - P308 + P313 - P391
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable