Furosemide

Empirical Formula (Hill Notation):	C12H11ClN2O5S
CAS Number:	54-31-9
Molecular Weight:	330.74
EC Number:	200-203-6
MDL number:	MFCD00010549
PubChem Substance ID:	329823087
NACRES:	NA.24

Кат. номер

PHR1057-1G

PHR1057-1G-PW

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Furosemide is a diuretic drug, which finds a variety of therapeutic applications such as hepatic cirrhosis, cardiac insufficiency and arterial hypertension.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Furosemide is classified under the group of loop diuretics. It is used for the prevention of hypertension linked to renal and cardiac insufficiency.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Furosemide may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by fluorimetry, spectrophotometry and high performance liquid chromatography (HPLC).
Furosemide may also be used as a reference standard in determining the concentration of furosemide present in human urine samples using gas chromatography coupled with mass spectrometry (GC-MS). Furosemide may be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using diffuse reflectance spectroscopy.
Inhibits ion co-transport in the kidney.
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA7130 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
form	neat
CofA	current certificate can be downloaded
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	220 °C (dec.) (lit.)
Featured Industry	Forensics and Toxicology Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to BP 547, traceable to PhEur F0700000, traceable to USP 1287008
SMILES string	NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl
InChI	1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)
InChI key	ZZUFCTLCJUWOSV-UHFFFAOYSA-N
Gene Information	human ... SLC12A1(6557)

pictograms	GHS07,GHS08
signalword	Danger
hcodes	H302 - H360FD
pcodes	P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3