Fluticasone Propionate

Empirical Formula (Hill Notation):	C25H31F3O5S
CAS Number:	80474-14-2
Molecular Weight:	500.57
MDL number:	MFCD00866007
PubChem Substance ID:	329823565
NACRES:	NA.24

Кат. номер

PHR1702-200MG

PHR1702-200MG-PW

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Fluticasone Propionate, a neutral, highly potent trifluorinated corticosteroid, is a component of aqueous nasal sprays. It shows potent topical anti-inflammatory activity and is highly efficient in suppressing the nasal symptoms associated with rhinitis and asthma.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Fluticasone Propionate may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and plasma samples by various chromatography techniques.
Fluticasone propionate is a second generation glucocorticoid. Used as an anti-inflammatory agent for asthma. Shown to enhance eosinophil apoptosis in a concentration-dependent manner via the glucocorticoid receptor.
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB9941 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
CofA	current certificate can be downloaded
packaging	pkg of 200 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to BP 587, traceable to PhEur Y0000284, traceable to USP 1285873
SMILES string	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
InChI	1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
InChI key	WMWTYOKRWGGJOA-CENSZEJFSA-N
Gene Information	human ... NR3C1(2908)

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable