Betamethasone

Empirical Formula (Hill Notation):	C22H29FO5
CAS Number:	378-44-9
Molecular Weight:	392.46
EC Number:	206-825-4
MDL number:	MFCD00062969
PubChem Substance ID:	329823372

Кат. номер

PHR1398-1G

PHR1398-1G-PW

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Betamethasone belongs to the corticosteriod family of active pharmaceutical ingredients (APIs). It exhibits anti-inflammatory activity and hence is used in the manufacture of various finished pharmaceutical products and is also employed as a starting material to manufacture other APIs that are related to this steroid family.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Betamethasone may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations by using micellar liquid chromatography technique and reversed-phase high-performance liquid chromatography technique.
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA2174 in the slot below. This is an example certificate only and may not be the lot that you receive.

Quality Level	300
biological source	synthetic
grade	certified reference material, pharmaceutical secondary standard
Agency/Method	BP, EP, USP
vapor pressure	<0.0000001 kPa ( 25 °C)
form	neat
CofA	current certificate can be downloaded
packaging	pkg of 1 g
storage condition	protect from light (20 mm aluminium crimp seal for unused portion)
application(s)	HPLC: suitable, gas chromatography (GC): suitable
color	white to light yellow
mp	235-237 °C (lit.)
solubility	acetone: sparingly soluble, chloroform: very slightly soluble, ethanol: sparingly soluble, ether: very slightly soluble, methanol: sparingly soluble, water: insoluble
density	0.305 g/cm3 at 25 °C (77°F)
Featured Industry	Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to BP 575, traceable to PhEur B1000000, traceable to USP 1066009
shipped in	ambient
SMILES string	[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
InChI	1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
InChI key	UREBDLICKHMUKA-DVTGEIKXSA-N
Gene Information	human ... NR3C1(2908)

pictograms	GHS08
signalword	Danger
hcodes	H360FD - H373
pcodes	P202 - P260 - P280 - P308 + P313 - P405 - P501
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable