Cisplatin
| Empirical Formula (Hill Notation): | H6Cl2N2Pt |
| Linear Formula: | Pt(NH3)2Cl2 |
| CAS Number: | 15663-27-1 |
| Molecular Weight: | 300.05 |
| EC Number: | 239-733-8 |
| MDL number: | MFCD00011623 |
| PubChem Substance ID: | 329823516 |
| NACRES: | NA.24 |
| Кат. номер |
| PHR1624-200MG |
| PHR1624-200MG-PW |
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Cisplatin is an antineoplastic drug used for the treatment of cancer patients with a variety of different malignancies.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Cisplatin may be used as an analytical reference standard for the determination of the analyte in plasma, cancer cell, and tumor samples by high-performance liquid chromatographic assay.
Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
This Certified Reference Material (CRM) is produced and certified in accordance with
ISO 17034 and
ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAB7778 in the slot below. This is an example certificate only and may not be the lot that you receive.
| Quality Level | 300 |
| grade | certified reference material, pharmaceutical secondary standard |
| CofA | current certificate can be downloaded |
| packaging | pkg of 200 mg |
| application(s) | HPLC: suitable, gas chromatography (GC): suitable |
| mp | 270 °C (lit.) |
| Featured Industry | Pharmaceutical (small molecule) |
| format | neat |
| pharmacopeia traceability | traceable to PhEur C2210000, traceable to USP 1134357 |
| SMILES string | N.N.Cl[Pt]Cl |
| InChI | 1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2 |
| InChI key | LXZZYRPGZAFOLE-UHFFFAOYSA-L |
| pictograms | GHS06,GHS08 |
| signalword | Danger |
| hcodes | H300 - H315 - H317 - H319 - H334 - H335 - H350 |
| pcodes | P201 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338 |
| Target Organs | Respiratory system |
| RIDADR | UN 3288 6.1 / PGII |
| WGK Germany | WGK 3 |
| Flash Point F | Not applicable |
| Flash Point C | Not applicable |