Solid Formulation
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Choline chloride
Empirical Formula (Hill Notation): C5H14ClNO CAS Number: 67-48-1 Molecular Weight: 139.62 MDL number: MFCD00011721 EC Index Number: 200-655-4
Кат. номер 5001175000 5001179010 5001179025 5001179999 5001170000 5001179825 5.00117.9025 5.00117.5000 General descriptionFinding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.ApplicationCholine chloride Emprove® Essential is mainly used in highly regulated pharmaceutical applications.Legal InformationEmprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store at +15°C to +25°C. Quality Level 500, Agency/Method DAB 10 reg. compliance FCC product line EMPROVE® ESSENTIAL autoignition temp. 355 °C potency 3400 mg/kg LD50, oral (Rat) pH 4-6 (20 °C, 100 g/L in H2O) bulk density 430 kg/m3 storage temp. 15-25°C InChI 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1 InChI key SGMZJAMFUVOLNK-UHFFFAOYSA-M
Safety InformationWGK Germany WGK 1 Flash Point F Not applicable Flash Point C Not applicable Узнать цену -
Choline hydrogen tartrate
Empirical Formula (Hill Notation): C9H19NO7 CAS Number: 87-67-2 Molecular Weight: 253.25 EC Index Number: 201-763-4
Кат. номер 5001159825 5001159025 5001155000 5001159999 5.00115.9999 5.00115.5000 5001150000 General descriptionFinding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.ApplicationCholine hydrogen tartrate is an essential nutrient and typically grouped with B-complex vitamins.Legal InformationEmprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions no restrictions. Quality Level 500, Agency/Method DAB 10 reg. compliance FCC product line EMPROVE® ESSENTIAL pH 3.0-4.4 (20 °C, 50 g/L in H2O) mp 147-152 °C bulk density 475 kg/m3 storage temp. 15-25°C InChI 1S/C5H14NO.C4H6O6/c1-6(2,3)4-5-7;5-1(3(7)8)2(6)4(9)10/h7H,4-5H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/q+1;/p-1/t;1-,2-/m.1/s1 InChI key QWJSAWXRUVVRLH-LREBCSMRSA-M Узнать цену -
Kieselguhr
CAS Number: 68855-54-9 MDL number: MFCD00132803 EC Index Number: 272-489-0
Кат. номер 1081170000 1081179026 1081179999 1081179025 1.08117.9025 General descriptionFinding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.ApplicationKieselguhr purified and calcined Emprove® Essential is mainly used in highly regulated pharmaceutical applications in oral administration.Legal InformationEmprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions no restrictions. Agency/Method NF Quality Level 500, product line EMPROVE® ESSENTIAL pH 10 (20 °C, 100 g/L in H2O) mp >450 °C solubility 0.0037 g/L density 2.36 g/cm3 at 20 °C bulk density 300 kg/m3 storage temp. 2-30°C Узнать цену -
Pancreatin
CAS Number: 8049-47-6 MDL number: MFCD00131789 EC Index Number: 232-468-9
Кат. номер 1071330000 1071339999 1071335000 General descriptionWe offer a range of high quality critical raw materials, solvents and reagents plus the documentation and expertise to meet stringent regulatory requirements. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.ApplicationPancreatin is a digestive enzyme used to supplement the bodys natural supply of such enzymes. Pancreatin Emprove® Essential is suitable for pharmaceutical applications.Legal InformationEmprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, GermanyПараметрыstorage conditions Store below +15°C. Agency/Method Ph. Eur., USP Quality Level 500 product line EMPROVE® ESSENTIAL form fine powder autoignition temp. >360 °C potency >10000 mg/kg LD50, oral (Rat) pH 5-6 (20 °C, 10 g/L in H2O) bulk density 400 kg/m3 storage temp. 2-8°C Узнать цену -
Sucralose powder
Empirical Formula (Hill Notation): C12H19Cl3O8 CAS Number: 56038-13-2 Molecular Weight: 397.63 Beilstein/REAXYS Number: 3654410 MDL number: MFCD03648615 EC Index Number: 259-952-2
Кат. номер 1008940000 1008940010 1008941000 1008949011 1008940011 1008941001 1008949010 General descriptionFinding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.ApplicationSucralose is a high-intensity sweetener which is non-cariogenic and suitable for diabetics and patients with an impaired glucose tolerance. In addition, it is readily soluble and masks both bitterness and medicinal off-notes with equal ease – making it exceptionally well-suited for pharmaceutical applications.
Our Sucralose is available in micronized or granular form, both pharmaceutical grade, allowing you to choose depending on your individual needs. Due to its optimal dispersion behavior, sucralose powder is typically recommended for solid dose formulations, while the fast dissolution behavior of sucralose granular makes it very well-suited for liquid formulations.Biochem/physiol ActionsA synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.Legal InformationEmprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, GermanyDisclaimerThe substance 1.00894 has no REACH registration because the only supported use is the use in medicinal products for human or veterinary use or in food or feedingstuffs according to article 2 of the REACH Regulation (EC) No 1907/2006.Параметрыstorage conditions Store at +15°C to +25°C. Quality Level 500 Agency/Method ChP, JPE, NF, Ph. Eur. description EMPROVE® ESSENTIAL Ph Eur,NF,JPE product line EMPROVE® ESSENTIAL form powder, crystals or beads potency >10000 mg/kg LD50, oral (Rat) pH 6-8 (20 °C, 100 g/L in H2O) mp 130 °C (decomposition) density 1.62 g/cm3 at 20 °C storage temp. 15-25°C SMILES string OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl InChI 1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1 InChI key BAQAVOSOZGMPRM-QBMZZYIRSA-N Узнать цену
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