Зачем лаборатории нужны стандарты пищевых добавок?

Они используются для калибровки оборудования, валидации методик и точного количественного определения добавок в сырье и готовой продукции.

Можно ли использовать одну стандартную смесь для разных продуктов?

Это возможно при подтверждённой совместимости методики и отсутствии выраженных матричных эффектов, однако для разных типов продукции может потребоваться отдельная валидация.

Почему важна высокая чистота стандартных образцов?

Высокая чистота снижает риск аналитических искажений и обеспечивает корректную калибровку и достоверность количественных результатов.

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(+)--Tocopherol 47785

Empirical Formula (Hill Notation):	C₂₈H₄₈O₂
CAS Number:	54-28-4
Molecular Weight:	416.68
Beilstein/REAXYS Number:	93072
EC Number:	200-201-5
MDL number:	MFCD00066529
PubChem Substance ID:	24871422
E Number:	E308

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
form	neat, solid
CofA	current certificate can be downloaded
packaging	ampule of 25 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule) Vitamins, Nutraceuticals, and Natural Products
format	neat
storage temp.	20°C
SMILES string	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1
InChI	1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/m1/s1
InChI key	QUEDXNHFTDJVIY-DQCZWYHMSA-N
Gene Information	human ... HMGCR(3156)

Safety Information

Personal Protective Equipment	Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

274,50 евро / 25 743 руб.

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(+)-Sodium L-ascorbate

Empirical Formula (Hill Notation):	C₆H₇NaO₆
CAS Number:	134-03-2
Molecular Weight:	198.11
Beilstein/REAXYS Number:	3767246
EC Number:	205-126-1
MDL number:	MFCD00082340
PubChem Substance ID:	329748045
NACRES:	NA.24

(+)-Sodium L-ascorbate is a sodium salt of ascorbic acid.

Application

Sodium ascorbate has been used as a reference standard for the determination of sodium ascorbate in polyvitaminated premixes utilized for the fortification of infant nutrition products by reversed-phase high performance liquid chromatography (RP-HPLC) combined with ultra-violet (UV) detection and in pharmaceutical formulations by RP-ion pair LC method. (+)-Sodium L-ascorbate may be used as an analytical standard for the identification and quantification of (+)-sodium L-ascorbate as a ferric ion chelator (FIC) by HPLC post-column method with fluorescence detection.

Параметры

Quality Level	100
grade	analytical standard
assay	98.5% (TLC), 10.8-12.8% Na basis
shelf life	limited shelf life, expiry date on the label
application(s)	detection: suitable
loss	2.0% loss on drying
mp	220 °C (dec.) (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	[Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]
InChI	1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1
InChI key	PPASLZSBLFJQEF-RXSVEWSESA-M

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

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(±)--Tocopherol 47783

Empirical Formula (Hill Notation):	C₂₉H₅₀O₂
CAS Number:	10191-41-0
Molecular Weight:	430.71
Beilstein/REAXYS Number:	94012
EC Number:	233-466-0
MDL number:	MFCD00006848
PubChem Substance ID:	24871420
E Number:	E307

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
(±)-α-Tocopherol may be used as an analytical reference standard for the quantification of the analyte in biological samples using different chromatography techniques.

Параметры

Quality Level	100
grade	analytical standard
form	neat, solid
CofA	current certificate can be downloaded
feature	standard type fat soluble vitamin
packaging	ampule of 100 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
density	0.950 g/mL at 20 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule) Vitamins, Nutraceuticals, and Natural Products
format	neat
storage temp.	20°C
SMILES string	CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1
InChI	1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3
InChI key	GVJHHUAWPYXKBD-UHFFFAOYSA-N

Safety Information

Pictograms	GHS07
Signal Word	Warning
Hazard Statements	H317
Precautionary Statements	P261 - P272 - P280 - P333 + P313 - P362 + P364 - P501
Personal Protective Equipment	Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	235.4 °F - closed cup
Flash Point(C)	113 °C - closed cup

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-Carotene

Empirical Formula (Hill Notation):	C₄₀H₅₆
CAS Number:	7235-40-7
Molecular Weight:	536.87
Beilstein/REAXYS Number:	1917416
EC Number:	230-636-6
MDL number:	MFCD00001556
PubChem Substance ID:	329823244
NACRES:	NA.24

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
-Carotene is an antioxidant and is one of the most important carotenoids and a source of vitamin A. It is abundantly present in fruits and vegetables which is also used as a food supplement and a colorant.

Application

β-Carotene may be used as a pharmaceutical reference standard for the determination of the analyte in serum, plasma samples, fruits and vegetables by various chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

The most important of the provitamins A, -carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0284 in the slot below. This is an example certificate only and may not be the lot that you receive.

Параметры

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
form	neat, solid
CofA	current certificate can be downloaded
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to USP 1065480
SMILES string	CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1
InChI	1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
InChI key	OENHQHLEOONYIE-JLTXGRSLSA-N

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	217.9 °F - closed cup
Flash Point(C)	103.3 °C - closed cup

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-Tocopherol 47784

Empirical Formula (Hill Notation):	C₂₇H₄₆O₂
CAS Number:	119-13-1
Molecular Weight:	402.65
EC Number:	204-299-0
MDL number:	MFCD20486794
PubChem Substance ID:	24871421
E Number:	E309

General description

δ-Tocopherol, a homolog of vitamin E, is a phytochemical with potent antioxidant activity. It has been investigated for its potential medical, biological, and physio-chemical applications.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
δ-Tocopherol may be used as an analytical reference standard for the determination of the analyte in food and beverage products and crops by high-performance liquid chromatography technique.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 47784.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Параметры

Quality Level	100
grade	analytical standard
form	neat, solid
CofA	current certificate can be downloaded
feature	standard type fat soluble vitamin
packaging	ampule of 100 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule) Vitamins, Nutraceuticals, and Natural Products
format	neat
storage temp.	20°C
SMILES string	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)cc(C)c2O1
InChI	1S/C27H46O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h18-22,28H,7-17H2,1-6H3/t21-,22-,27-/m1/s1
InChI key	GZIFEOYASATJEH-VHFRWLAGSA-N

Safety Information

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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2-Phenylphenol

Empirical Formula (Hill Notation):	C₁₂H₁₀O
Linear Formula:	C₆H₅C₆H₄OH
CAS Number:	90-43-7
Molecular Weight:	170.21
Beilstein/REAXYS Number:	606907
EC Number:	201-993-5
MDL number:	MFCD00002208
PubChem Substance ID:	329756814
E Number:	E232
NACRES:	NA.24

2-Phenylphenol is a bactericide, disinfectant and virucide with low levels of toxicity. It is commonly used in agriculture, for disinfecting fruits, eggs, and vegetables. 2-Phenylphenol also finds applications as a surface disinfectant in hospitals, veterinary centers, nursing homes, poultry farms, commercial laundries, food processing plants, dairy farms, etc.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
2-Phenylphenol may be used as an analytical reference standard for the quantification of the analyte in sewage, sludge, sediments and commercial formulations using chromatography techniques.

Legal Information

PESTANAL is a registered trademark of Sigma-Aldrich International GmbH

Параметры

Quality Level	100
grade	analytical standard
vapor pressure	7 mmHg ( 140 °C)
product line	PESTANAL^®
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
bp	282 °C (lit.)
mp	57-59 °C (lit.)
Featured Industry	Agriculture Cleaning Products Cosmetics Environmental Flavors and Fragrances Food and Beverages Personal Care
format	neat
SMILES string	Oc1ccccc1-c2ccccc2
InChI	1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H
InChI key	LLEMOWNGBBNAJR-UHFFFAOYSA-N

Safety Information

pictograms	GHS07,GHS09
signalword	Warning
hcodes	H315 - H319 - H335 - H400
pcodes	P273 - P302 + P352 - P305 + P351 + P338
Target Organs	Respiratory system
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 2
Flash Point F	255.2 °F - closed cup
Flash Point C	124 °C - closed cup

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3,5-Di-tert-4-butylhydroxytoluene (BHT) 47168

CAS Number:	128-37-0
EC Number:	204-881-4
MDL number:	MFCD00011644
PubChem Substance ID:	24870753

General description

3,5-Di-tert-4-butylhydroxytoluene belongs to the class of phenolic antioxidants, added to food and other products such as oils, fats and butter oil to prevent rancidity caused by the oxidation of unsaturated fats.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
3,5-Di-tert-4-butylhydroxytoluene may be used as an analytical reference standard for the quantification of the analyte in Eucalyptus wood using chromatography techniques.

Параметры

Quality Level	100
grade	analytical standard
form	neat
CofA	current certificate can be downloaded
packaging	pkg of 500 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	room temp
SMILES string	Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
InChI	1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3
InChI key	NLZUEZXRPGMBCV-UHFFFAOYSA-N
Gene Information	human ... CAPN1(823) rat ... Capn1(29153), Nos1(24598)

Safety Information

Pictograms	GHS09
Signal Word	Warning
Hazard Statements	H410
Precautionary Statements	P273
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 2
Flash Point(F)	260.6 °F - open cup
Flash Point(C)	127 °C - open cup

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6-O-Palmitoyl-L-ascorbic acid

Empirical Formula (Hill Notation):	C₂₂H₃₈O₇
CAS Number:	137-66-6
Molecular Weight:	414.53
Beilstein/REAXYS Number:	96552
EC Number:	205-305-4
MDL number:	MFCD00005377
PubChem Substance ID:	329747391
NACRES:	NA.24

Quality Level	100
grade	analytical standard
assay	98.5% (HPLC)
form	powder or crystals
shelf life	limited shelf life, expiry date on the label
loss	2.0% loss on drying
color	white to light beige
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
InChI	1S/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,21,23,25-26H,2-16H2,1H3/t17-,21+/m0/s1
InChI key	QAQJMLQRFWZOBN-LAUBAEHRSA-N

Safety Information

pictograms	GHS07
signalword	Warning
hcodes	H319
pcodes	P264 - P280 - P305 + P351 + P338 - P337 + P313
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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Allura Red AC

Empirical Formula (Hill Notation):	C₁₈H₁₄N₂Na₂O₈S₂
CAS Number:	25956-17-6
Molecular Weight:	496.42
Colour Index Number:	16035
EC Number:	247-368-0
MDL number:	MFCD00059526
PubChem Substance ID:	329755751
E Number:	E129
NACRES:	NA.24

Allura Red AC belongs to the class of monoazo dyes. It comprises of 6-hydroxy-5-(2-methoxy-5-methyl-4-sulfonate-phenylazo)-2-napthalene-sulfonate, which is basically an azo-coupling product between the meta-isomer of cresidine-p-sulphonic acid (CSA) and Schaeffers salt (SS). It exists in the form of dark red powder or granules and finds application in being used in food colors. It is soluble in water and is insoluble in ethanol.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

Параметры

grade	analytical standard
Quality Level	100
assay	98.0% (HPLC)
form	neat
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	>300 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	[Na+].[Na+].COc1cc(c(C)cc1\N=N\c2c(O)ccc3cc(ccc23)S([O-])(=O)=O)S([O-])(=O)=O
InChI	1S/C18H16N2O8S2.2Na/c1-10-7-14(16(28-2)9-17(10)30(25,26)27)19-20-18-13-5-4-12(29(22,23)24)8-11(13)3-6-15(18)21;;/h3-9,21H,1-2H3,(H,22,23,24)(H,25,26,27);;/q;2*+1/p-2/b20-19+;;
InChI key	CEZCCHQBSQPRMU-LLIZZRELSA-L

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Aluminum standard for AAS

Empirical Formula (Hill Notation):	AlCl₃
CAS Number:	7446-70-0
Molecular Weight:	133.34
MDL number:	MFCD00003422
eCl@ss:	38120507
PubChem Substance ID:	329748214
E Number:	E173
NACRES:	NA.24

Aluminum standard for AAS may be used for the determination of total aluminum content and the fraction of aluminum leached to the infusions of black tea, green tea, Hibiscus sabdariffa, and Ilex paraguariensis (mate) and for the analysis of aluminum in drinking water, in foods and beverages consumed in the Spanish diet as well as in lubricating oils by electrothermal atomic absorption spectrometry (ET-AAS).

Preparation Note

prepared with AlCl3 and HCl (~0.05 M)

Параметры

grade	analytical standard
Quality Level	100
shelf life	limited shelf life, expiry date on the label
concentration	1.0 g/L Al in hydrochloric acid
application(s)	AAS: suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	single component solution
SMILES string	Cl[Al](Cl)Cl
InChI	1S/Al.3ClH/h;3*1H/q+3;;;/p-3
InChI key	VSCWAEJMTAWNJL-UHFFFAOYSA-K

Safety Information

pictograms	GHS05
signalword	Warning
hcodes	H290
pcodes	P234 - P390
Personal Protective Equipment	Eyeshields, Gloves
RIDADR	UN 3264 8 / PGIII
WGK Germany	nwg
Flash Point F	Not applicable
Flash Point C	Not applicable

422,83 евро / 39 654 руб.

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Aspartame 47135

Empirical Formula (Hill Notation):	C₁₄H₁₈N₂O₅
Linear Formula:	HOOCCH₂CH(NH₂)CONHCH(CH₂C₆H₅)COOCH₃
CAS Number:	22839-47-0
Molecular Weight:	294.30
Beilstein/REAXYS Number:	2223850
EC Number:	245-261-3
MDL number:	MFCD00002724
PubChem Substance ID:	24870725
E Number:	E951

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 47135.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Параметры

Quality Level	100
grade	analytical standard
form	neat
CofA	current certificate can be downloaded
packaging	pkg of 500 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	2-8°C
SMILES string	COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(O)=O
InChI	1S/C14H18N2O5/c1-21-14(20)11(7-9-5-3-2-4-6-9)16-13(19)10(15)8-12(17)18/h2-6,10-11H,7-8,15H2,1H3,(H,16,19)(H,17,18)/t10-,11-/m0/s1
InChI key	IAOZJIPTCAWIRG-QWRGUYRKSA-N

Safety Information

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Bacitracin A

Empirical Formula (Hill Notation):	C₆₆H₁₀₃N₁₇O₁₆S
Molecular Weight:	1422.69
EC Number:	245-115-9
PubChem Substance ID:	24869751
E Number:	E700
NACRES:	NA.24

Bacitracin is a polypeptide antibiotic produced by strains of Bacillus subtilis and Bacillus licheniformis. Bacitracin A is a commercially produced, major microbiologically active component of bacitracin.

Application

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Параметры

grade	analytical standard
Quality Level	100
product line	VETRANAL^®
form	neat
shelf life	limited shelf life, expiry date on the label
composition	main stereoisomer, ~50%
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	2-8°C
SMILES string	CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)NC([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)C(NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC

Safety Information

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

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Brilliant Blue FCF

Empirical Formula (Hill Notation):	C₃₇H₃₄Na₂N₂O₉S₃
CAS Number:	3844-45-9
Molecular Weight:	792.85
Colour Index Number:	42090
EC Number:	223-339-8
MDL number:	MFCD00012141
PubChem Substance ID:	329769043
NACRES:	NA.24

Brilliant blue FCF has been used as a test compound in validating the lowest observed adverse effect level (LOAEL) to inflict developmental toxicity upon exposure to common excipients.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
assay	97.0% (HPLC)
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	283 °C (dec.) (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	[Na+].[Na+].CCN(Cc1cccc(c1)S([O-])(=O)=O)c2ccc(cc2)C(=C3\C=C/C(C=C3)=[N+](\CC)Cc4cccc(c4)S([O-])(=O)=O)\c5ccccc5S([O-])(=O)=O
InChI	1S/C37H36N2O9S3.2Na/c1-3-38(25-27-9-7-11-33(23-27)49(40,41)42)31-19-15-29(16-20-31)37(35-13-5-6-14-36(35)51(46,47)48)30-17-21-32(22-18-30)39(4-2)26-28-10-8-12-34(24-28)50(43,44)45;;/h5-24H,3-4,25-26H2,1-2H3,(H2-,40,41,42,43,44,45,46,47,48);;/q;2*+1/p-2
InChI key	SGHZXLIDFTYFHQ-UHFFFAOYSA-L

Safety Information

Hazard Statements	H412
Precautionary Statements	P273
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Butylated hydroxyanisole

Empirical Formula (Hill Notation):	C₁₁H₁₆O₂
Linear Formula:	(CH₃)₃CC₆H₃(OCH₃)OH
CAS Number:	25013-16-5
Molecular Weight:	180.24
EC Number:	246-563-8
MDL number:	MFCD01779059
E Number:	E320
NACRES:	NA.24

Butylated hydroxyanisole (BHA), a lipophilic compound, is reported to exhibit antimicrobial activity against molds and Gram-positive bacteria. It also finds applications as a direct/indirect additive in adhesives, lubricants, food packaging materials, defoaming agents, as a preservative in cosmetic products, antioxidant in petroleum products including jet fuels, cutting oils, rubber latex gloves, paints, lacquers, adhesive hardeners, cleaning agents, thinners, plastics, etc. It is also widely used as an antioxidant in food industry.††

Application

Butylated hydroxyanisole may be used as an analytical reference standard for the quantification of the analyte in the following:

Food samples using square-wave voltammetry (SWV), further confirmed by high-performance liquid chromatography technique (HPLC) and capillary electrophoresis (CE) coupled with end-column amperometric detection.
Cosmetics using fluorescence spectroscopy with second-order calibration, further confirmed by HPLC technique.

Параметры

Quality Level	100
grade	analytical standard
vapor density	6.2 (vs air)
assay	99.0% (sum of isomers, GC)
form	neat
autoignition temp.	599 °F
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	58-60 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
InChI	1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3
InChI key	MRBKEAMVRSLQPH-UHFFFAOYSA-N

Safety Information

pictograms	GHS07,GHS09
signalword	Warning
hcodes	H302 - H411
pcodes	P264 - P270 - P273 - P301 + P312 - P391 - P501
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	241.9 °F - Pensky-Martens closed cup
Flash Point C	116.6 °C - Pensky-Martens closed cup

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Butylated Hydroxytoluene

Empirical Formula (Hill Notation):	C₁₅H₂₄O
Linear Formula:	[(CH₃)₃C]₂C₆H₂(CH₃)OH
CAS Number:	128-37-0
Molecular Weight:	220.35
Beilstein/REAXYS Number:	1911640
EC Number:	204-881-4
MDL number:	MFCD00011644
PubChem Substance ID:	329823138
E Number:	E321
NACRES:	NA.24

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Butylated hydroxytoluene (BHT) is a phenolic antioxidant used as a food additive. It is frequently added to dried cereals, cooking oils and animal foods. BHT is also known to enhance the stability of pharmaceuticals, fat-soluble vitamins and cosmetics .

Application

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB3695 in the slot below. This is an example certificate only and may not be the lot that you receive.

Параметры

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
vapor density	7.6 (vs air)
vapor pressure	<0.01 mmHg ( 20 °C)
form	neat
CofA	current certificate can be downloaded
autoignition temp.	878 °F
application(s)	HPLC: suitable, gas chromatography (GC): suitable
bp	265 °C (lit.)
mp	69-73 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to PhEur B1215000, traceable to USP 1092708
SMILES string	Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
InChI	1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3
InChI key	NLZUEZXRPGMBCV-UHFFFAOYSA-N

Safety Information

Pictograms	GHS09
Signal Word	Warning
Hazard Statements	H410
Precautionary Statements	P273 - P391 - P501
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 2
Flash Point(F)	260.6 °F - open cup
Flash Point(C)	127 °C - open cup

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Бутилгидроксианизол EDQM

Эмпирическая формула (нотация Хилла):	C₁₁H₁₆O₂
Линейная формула:	(CH₃)₃CC₆H₃(OCH₃)OH
Номер CAS:	25013-16-5
Молекулярная масса:	180.24
Номер EC:	246-563-8
Номер MDL:	MFCD01779059
Номер E:	E320
NACRES:	NA.24

Данный продукт предоставляется в том виде, в каком он был поставлен и указан соответствующей Фармакопеей. Вся информация, предоставленная в поддержку данного продукта, включая SDS и любые информационные листки, была разработана и выпущена под эгидой соответствующей Фармакопеи.

Упаковка

Количество единиц: 60 мг. Может быть изменено. Продукт поставляется в том виде, в каком он был предоставлен соответствующей Фармакопеей.

Другие примечания

Могут применяться ограничения на продажу.

Параметры

качество	фармацевтический первичный стандарт
плотность пара	6.2 (по воздуху)
форма	чистый
температура самовоспламенения	599 °F
Торговая марка	EDQM
т.пл.	58-60 °C (лит.)
Основные отрасли	Моющие средства Косметика Пищевые продукты и напитки Средства личной гигиены Фармацевтика (малые молекулы)
формат	чистый
InChI	1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3
Ключ InChI	MRBKEAMVRSLQPH-UHFFFAOYSA-N

Информация по безопасности

пиктограммы	GHS07,GHS09
сигнальное

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Chlorophyll a

Empirical Formula (Hill Notation):	C₅₅H₇₂MgN₄O₅
CAS Number:	479-61-8
Molecular Weight:	893.49
Beilstein/REAXYS Number:	3586237
EC Number:	207-536-6
MDL number:	MFCD00079050

Chlorophyll a is present as a key pigment in organisms with oxygenic photosynthesis. It functions as an antenna pigment in both reaction centers I and II.

Application

A procedure has been described for harvesting native light-harvesting complex IIb (LHCIIb).

Параметры

grade	analytical standard
Quality Level	100
assay	95.0% (HPLC)
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	20°C
SMILES string	CCc1c(C)c2cc3c(C=C)c(C)c4cc5nc([C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@@H]5C)c6[C@@H](C(=O)OC)C(=O)c7c(C)c(cc1n2)n([Mg]n34)c67
InChI	1S/C55H73N4O5.Mg/c1-13-39-35(8)42-28-44-37(10)41(24-25-48(60)64-27-26-34(7)23-17-22-33(6)21-16-20-32(5)19-15-18-31(3)4)52(58-44)50-51(55(62)63-12)54(61)49-38(11)45(59-53(49)50)30-47-40(14-2)36(9)43(57-47)29-46(39)56-42;/h13,26,28-33,37,41,51H,1,14-25,27H2,2-12H3,(H-,56,57,58,59,61);/q-1;+2/p-1/b34-26+;/t32-,33-,37+,41+,51-;/m1./s1
InChI key	ATNHDLDRLWWWCB-AENOIHSZSA-M

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Холевая кислота EDQM

Эмпирическая формула (нотация Хилла):	C₂₄H₄₀O₅
Номер CAS:	81-25-4
Молекулярная масса:	408.57
Номер Beilstein/REAXYS:	2822009
Номер MDL:	MFCD00003672
ID вещества в PubChem:	329774969
NACRES:	NA.24

Неденaтурирующее ионное детергентное средство, используемое для экстракции мембранных белков.

Биохимическое/физиологическое действие

Желчная кислота

Упаковка

Другие примечания

Могут применяться ограничения на продажу.

Параметры

качество	фармацевтический первичный стандарт
Организация/Метод	Стандарт-образец EP
форма	чистый
Торговая марка	EDQM
т.пл.	200-201 °C (лит.)
Основные отрасли	Моющие средства Косметика Пищевые продукты и напитки Средства личной гигиены Фармацевтика (малые молекулы)
формат	чистый
SMILES-строка	[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(O)=O
InChI	1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1
Ключ InChI	BHQCQFFYRZLCQQ-OELDTZBJSA-N

Информация по безопасности

RIDADR	Неопасный груз для всех видов транспорта
Класс опасности по Германии (WGK)	WGK 2
Температура вспышки (°F)	Не применимо
Температура вспышки (°C)	Не применимо

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Citric acid 46933

Empirical Formula (Hill Notation):	C₆H₈O₇
Linear Formula:	HOC(COOH)(CH₂COOH)₂
CAS Number:	77-92-9
Molecular Weight:	192.12
Beilstein/REAXYS Number:	782061
EC Number:	201-069-1
MDL number:	MFCD00011669
PubChem Substance ID:	24870585
E Number:	E330

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
assay	99.5% (as is basis)
form	neat
CofA	current certificate can be downloaded
expl. lim.	8 %, 65 °F
packaging	pkg of 1000 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
pKa A	(1) 3.13, (2) 4.76, (3) 6.4
mp	153-159 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	room temp
SMILES string	OC(=O)CC(O)(CC(O)=O)C(O)=O
InChI	1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChI key	KRKNYBCHXYNGOX-UHFFFAOYSA-N
Gene Information	human ... SRC(6714)

Safety Information

pictograms	GHS07
signalword	Warning
hcodes	H319
pcodes	P264 - P280 - P305 + P351 + P338 - P337 + P313
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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Curcumin

Empirical Formula (Hill Notation):	C₂₁H₂₀O₆
Linear Formula:	[HOC₆H₃(OCH₃)CH=CHCO]₂CH₂
CAS Number:	458-37-7
Molecular Weight:	368.38
Colour Index Number:	75300
Beilstein/REAXYS Number:	2306965
EC Number:	207-280-5
MDL number:	MFCD00008365
PubChem Substance ID:	329748594
E Number:	E100
NACRES:	NA.24

Curcumin is an anti-inflammatory agent extracted from the roots of Curcuma longa Linn.

Application

Curcumin may be used as a reference standard for the determination of curcumin in rat plasma by high-performance liquid chromatography method.

Biochem/physiol Actions

A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Параметры

Quality Level	100
grade	analytical standard
vapor density	13 (vs air)
assay	98.0% (HPLC)
form	powder
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	2-8°C
SMILES string	COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
InChI	1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
InChI key	VFLDPWHFBUODDF-FCXRPNKRSA-N

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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D-Malic acid 46940-U

Empirical Formula (Hill Notation):	C₄H₆O₅
Linear Formula:	HO₂CCH₂CH(OH)CO₂H
CAS Number:	636-61-3
Molecular Weight:	134.09
Beilstein/REAXYS Number:	1723540
EC Number:	211-262-2
MDL number:	MFCD00004245
PubChem Substance ID:	329757271
E Number:	E296
NACRES:	NA.24

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
form	neat
CofA	current certificate can be downloaded
packaging	ampule of 100 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	98-102 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	room temp
SMILES string	O[C@H](CC(O)=O)C(O)=O
InChI	1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m1/s1
InChI key	BJEPYKJPYRNKOW-UWTATZPHSA-N

Safety Information

pictograms	GHS05, GHS07
signalword	Danger
hcodes	H315-H318-H335
pcodes	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	3

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D-Sorbitol 47841

Empirical Formula (Hill Notation):	C₆H₁₄O₆
CAS Number:	50-70-4
Molecular Weight:	182.17
Beilstein/REAXYS Number:	1721899
EC Number:	200-061-5
MDL number:	MFCD00004708
PubChem Substance ID:	24871505
E Number:	E420

General description

D-Sorbitol is a sugar alcohol, widely used as a food additive because of its advantages over parent sugars such as low cariogenicity, low calories and high thermostability.

Application

D-Sorbitol may be used as an analytical reference standard for the quantification of the analyte in foodstuffs using ion chromatography with polarized photometric detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
vapor density	<1 (vs air)
vapor pressure	<0.1 mmHg ( 25 °C)
form	neat
CofA	current certificate can be downloaded
packaging	pkg of 1 g
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	98-100 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	room temp
SMILES string	OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO
InChI	1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
InChI key	FBPFZTCFMRRESA-JGWLITMVSA-N

Safety Information

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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DL-Malic acid

Empirical Formula (Hill Notation):	C₄H₆O₅
Linear Formula:	HO₂CCH₂CH(OH)CO₂H
CAS Number:	6915-15-7
Molecular Weight:	134.09
Beilstein/REAXYS Number:	1723539
EC Number:	230-022-8
MDL number:	MFCD00064212
PubChem Substance ID:	329770397

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
vapor density	4.6 (vs air)
vapor pressure	<0.1 mmHg ( 20 °C)
assay	95.0-105.0 wt. % (NaOH 0.1M, T)
form	neat
autoignition temp.	644 °F
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	131-133 °C (lit.)
solubility	H₂O: soluble 646.6 g/L at 20 °C
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care
format	neat
storage temp.	2-8°C
SMILES string	OC(CC(O)=O)C(O)=O
InChI	1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)
InChI key	BJEPYKJPYRNKOW-UHFFFAOYSA-N

Safety Information

pictograms	GHS07
signalword	Warning
hcodes	H319
pcodes	P264 - P280 - P305 + P351 + P338 - P337 + P313
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	397.4 °F
Flash Point C	203 °C

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Эритрит EDQM

Эмпирическая формула (нотация Хилла):	C₄H₁₀O₄
Линейная формула:	HOCH₂[CH(OH)]₂CH₂OH
Номер CAS:	149-32-6
Молекулярная масса:	122.12
Номер Beilstein/REAXYS:	1719753
Номер MDL:	MFCD00004710
ID вещества в PubChem:	329830873
NACRES:	NA.24

Данный продукт предоставляется в том виде, в каком он был поставлен и указан соответствующей Фармакопеей.

Биохимическое/физиологическое действие

Аллельные вариации гена Tas1r3 влияют на поведенческие вкусовые реакции на этот сахарный спирт, что позволяет предположить, что он является лигандом рецептора T1R3.

Упаковка

Количество единиц: 1020 мг. Может быть изменено. Продукт поставляется в том виде, в каком он был предоставлен соответствующей Фармакопеей.

Другие примечания

Могут применяться ограничения на продажу.

Параметры

качество	фармацевтический первичный стандарт
форма	чистый
Торговая марка	EDQM
т.кип.	329-331 °C (лит.)
т.пл.	118-120 °C (лит.)
Основные отрасли	Моющие средства Косметика Пищевые продукты и напитки Средства личной гигиены Фармацевтика (малые молекулы)
формат	чистый
температура хранения	2-8°C
SMILES-строка	OC[C@@H](O)[C@@H](O)CO
InChI	1S/C4H10O4/c5-1-3(7)4(8)2-6/h3-8H,1-2H2/t3-,4+
Ключ InChI	UNXHWFMMPAWVPI-ZXZARUISSA-N

Информация по безопасности

RIDADR	Неопасный груз для всех видов транспорта
Класс опасности по Германии (WGK)	WGK 3
Температура вспышки (°F)	Не применимо
Температура вспышки (°C)	Не применимо

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Ethoxyquin

Empirical Formula (Hill Notation):	C₁₄H₁₉NO
CAS Number:	91-53-2
Molecular Weight:	217.31
Beilstein/REAXYS Number:	158223
EC Number:	202-075-7
MDL number:	MFCD00023883
PubChem Substance ID:	329753793
E Number:	E324
NACRES:	NA.24

Ethoxyquin (EQ), an aromatic compound, is an antioxidant mostly used in animal and fish feeds. It is seen to inhibit carcinogenic effects of polycyclic aromatic hydrocarbons. Oxidation initiated by air, light or transition metals in unsaturated lipids can be stopped from propagation by EQ.

Application

EQ has been used as external standard in the determination of EQ and its major metabolite from Atlantic salmon tissues using HPLC with fluorescence detector.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Caution

Light sensitive: sensitive
Air sensitive: Handle under argon

Legal Information

PESTANAL is a registered trademark of Sigma-Aldrich International GmbH

Параметры

Quality Level	100
grade	analytical standard
product line	PESTANAL^®
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
density	1.03 g/mL at 20 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
shipped in	wet ice
storage temp.	2-8°C
SMILES string	CCOc1ccc2NC(C)(C)C=C(C)c2c1
InChI	1S/C14H19NO/c1-5-16-11-6-7-13-12(8-11)10(2)9-14(3,4)15-13/h6-9,15H,5H2,1-4H3
InChI key	DECIPOUIJURFOJ-UHFFFAOYSA-N

Safety Information

pictograms	GHS07
signalword	Warning
hcodes	H302
pcodes	P301 + P312 + P330
Personal Protective Equipment	Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

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Ethyl maltol

Empirical Formula (Hill Notation):	C₇H₈O₃
CAS Number:	4940-11-8
Molecular Weight:	140.14
EC Number:	225-582-5
MDL number:	MFCD00059795
PubChem Substance ID:	329770307
E Number:	E637

Ethyl maltol is a synthetic homologue of maltol, often found as flavor enhancers and it contributes to the fragrance of commercials products such as cereals, breads, malt beverages, coffee, soybeans and chocolate milk.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Ethyl maltol may be used as an analytical reference standard for the quantification of the analyte in food using spectrophotometric technique.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Параметры

Quality Level	100
grade	analytical standard
assay	98.0% (GC)
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	85-95 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care
format	neat
SMILES string	CCC1=C(O)C(=O)C=CO1
InChI	1S/C7H8O3/c1-2-6-7(9)5(8)3-4-10-6/h3-4,9H,2H2,1H3
InChI key	YIKYNHJUKRTCJL-UHFFFAOYSA-N

Safety Information

pictograms	GHS07
signalword	Warning
hcodes	H302
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Ethylparaben

Empirical Formula (Hill Notation):	C₉H₁₀O₃
Linear Formula:	HOC₆H₄CO₂C₂H₅
CAS Number:	120-47-8
Molecular Weight:	166.17
Beilstein/REAXYS Number:	1101972
EC Number:	204-399-4
MDL number:	MFCD00002353
eCl@ss:	39024522
PubChem Substance ID:	329823042
E Number:	E214
NACRES:	NA.24

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3158 in the slot below. This is an example certificate only and may not be the lot that you receive.

Параметры

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
form	neat
CofA	current certificate can be downloaded
application(s)	HPLC: suitable, gas chromatography (GC): suitable
bp	297-298 °C (lit.)
mp	114-117 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to PhEur E2425000, traceable to USP 1267000
SMILES string	CCOC(=O)c1ccc(O)cc1
InChI	1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3
InChI key	NUVBSKCKDOMJSU-UHFFFAOYSA-N

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Glycerin

Empirical Formula (Hill Notation):	C₃H₈O₃
Linear Formula:	HOCH₂CH(OH)CH₂OH
CAS Number:	56-81-5
Molecular Weight:	92.09
Beilstein/REAXYS Number:	635685
EC Number:	200-289-5
MDL number:	MFCD00004722
PubChem Substance ID:	329823051
NACRES:	NA.24

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Glycerin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and cosmetics by chromatography techniques.
Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gels sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7812 in the slot below. This is an example certificate only and may not be the lot that you receive.

Параметры

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
vapor density	3.1 (vs air)
vapor pressure	<1 mmHg ( 20 °C)
form	neat
CofA	current certificate can be downloaded
autoignition temp.	698 °F
application(s)	HPLC: suitable, gas chromatography (GC): suitable
refractive index	n20/D 1.474 (lit.)
bp	182 °C/20 mmHg (lit.)
mp	20 °C (lit.)
density	1.25 g/mL (lit.)
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to PhEur G0400000, traceable to USP 1295607
SMILES string	OCC(O)CO
InChI	1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
InChI key	PEDCQBHIVMGVHV-UHFFFAOYSA-N

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	390.2 °F - Pensky-Martens closed cup
Flash Point(C)	199 °C - Pensky-Martens closed cup

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Hexamethylenetetramine

Empirical Formula (Hill Notation):	C₆H₁₂N₄
CAS Number:	100-97-0
Molecular Weight:	140.19
Beilstein/REAXYS Number:	2018
EC Number:	202-905-8
MDL number:	MFCD00006895
PubChem Substance ID:	329758095
NACRES:	NA.24

Hexamethylenetetramine is an organic compound and drug, commonly used in the treatment of human urinary infections. It is also widely used as a raw material of explosive compounds and accelerator in rubber vulcanization.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Hexamethylenetetramine may be used as an analytical reference standard for the determination of the analyte in water samples and pharmaceutical formulations using analytical techniques.

Параметры

Quality Level	100
grade	analytical standard
vapor pressure	<0.01 mmHg ( 20 °C)
assay	99.0% (GC)
form	neat
autoignition temp.	770 °F
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
impurities	1.0% water
mp	280 °C (subl.) (lit.)
solubility	H₂O: soluble
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	C1N2CN3CN1CN(C2)C3
InChI	1S/C6H12N4/c1-7-2-9-4-8(1)5-10(3-7)6-9/h1-6H2
InChI key	VKYKSIONXSXAKP-UHFFFAOYSA-N

Safety Information

pictograms	GHS02,GHS07
signalword	Warning
hcodes	H228 - H317
pcodes	P210 - P280 - P302 + P352
RIDADR	UN1328 - class 4.1 - PG 3 - Hexamethylenetetramine
WGK Germany	WGK 1
Flash Point F	482.0 °F - closed cup
Flash Point C	250 °C - closed cup

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L-Ascorbic acid 47863

Empirical Formula (Hill Notation):	C₆H₈O₆
CAS Number:	50-81-7
Molecular Weight:	176.12
Beilstein/REAXYS Number:	84272
EC Number:	200-066-2
MDL number:	MFCD00064328
PubChem Substance ID:	24871532
E Number:	E300

General description

L-Ascorbic acid plays the role of an antioxidant in plants in regulating the reactive oxygen species mechanism to form reduced peroxides. It is present abundantly as a non-enzymatic antioxidant in higher plants. It can be synthesized in a variety of plants and in all known mammals, except primates and guinea pigs. It can commonly be used in the prevention of scurvy disease.

Application

L-Ascorbic acid may be used as an analytical reference standard for the quantification of the analyte in fruits and vegetable juice samples using flow injection system with immobilised ascorbate oxidase enzyme.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
form	neat, solid
CofA	current certificate can be downloaded
feature	standard type water soluble vitamin
packaging	ampule of 1000 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
pH	1.0-2.5 (25 °C, 176 g/L in water)
mp	190-194 °C (dec.)
solubility	water: soluble 176 g/L at 20 °C
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule) Vitamins, Nutraceuticals, and Natural Products
format	neat
storage temp.	2-8°C
SMILES string	OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
InChI	1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChI key	CIWBSHSKHKDKBQ-JLAZNSOCSA-N
Gene Information	human ... SLC23A2(9962)

Safety Information

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

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L-Glutamic acid monosodium salt hydrate

Empirical Formula (Hill Notation):	C₅H₈NNaO₄ · xH₂O
CAS Number:	142-47-2
Molecular Weight:	169.11 (anhydrous basis)
MDL number:	MFCD00013074
PubChem Substance ID:	329747308
E Number:	E620
NACRES:	NA.24

Кат. номер

1495-VAR

1495-1G

Biochem/physiol Actions

Agonist at kainate, NMDA, and quisqualate receptors; an excitatory amino acid neurotransmitter.

Параметры

Quality Level	100
grade	analytical standard
assay	98.5% (TLC)
shelf life	limited shelf life, expiry date on the label
impurities	9.62% water (theory, monohydrate)
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care
format	neat
InChI	1S/C5H9NO4.Na.H2O.H/c6-3(5(9)10)1-2-4(7)8;;;/h3H,1-2,6H2,(H,7,8)(H,9,10);;1H2;
InChI key	JYDGDQPVBSBYRT-UHFFFAOYSA-N

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

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Lauryl gallate

Empirical Formula (Hill Notation):	C₁₉H₃₀O₅
CAS Number:	1166-52-5
Molecular Weight:	338.44
Beilstein/REAXYS Number:	2701981
EC Number:	214-620-6
MDL number:	MFCD00002195
PubChem Substance ID:	329757911
E Number:	E312
NACRES:	NA.24

Lauryl gallate is a major monomer flavanol found in green tea and shows antioxidant activity in polymers.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Lauryl gallate may be used as an analytical standard in investigating its activity as a pro-ecological anti-ageing substance for common polymers as food packing materials using electroanalytical techniques such as cyclic voltammetry (CV) and differential pulse voltammetry (DPV) methods.

Параметры

Quality Level	100
grade	analytical standard
assay	99.0% (HPLC)
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	94-97 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	CCCCCCCCCCCCOC(=O)c1cc(O)c(O)c(O)c1
InChI	1S/C19H30O5/c1-2-3-4-5-6-7-8-9-10-11-12-24-19(23)15-13-16(20)18(22)17(21)14-15/h13-14,20-22H,2-12H2,1H3
InChI key	RPWFJAMTCNSJKK-UHFFFAOYSA-N

Safety Information

pictograms	GHS07
signalword	Warning
hcodes	H317
pcodes	P280
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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Maltol

Empirical Formula (Hill Notation):	C₆H₆O₃
CAS Number:	118-71-8
Molecular Weight:	126.11
Beilstein/REAXYS Number:	112169
EC Number:	204-271-8
MDL number:	MFCD00006578
PubChem Substance ID:	329751660
NACRES:	NA.24

Maltol is an important food additive, which finds applications as a potent flavor enhancer to modify or enhance the flavor in the food and beverage industry. Some of the sources of maltol include bread crusts, baked cereals, coffee, caramelized food products, pyrolysis of sucrose, etc.

Application

Maltol may be used as an analytical reference standard for the quantification of the analyte in:

Synthetic and commercial food samples using UV–Vis spectrophotometry with chemometrics methods.
Food and beverage matrices using FIA-direct chemiluminescence procedure.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
assay	97.0% (GC)
form	neat
autoignition temp.	1364 °F
shelf life	limited shelf life, expiry date on the label
expl. lim.	25 %
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	159-162 °C, 160-164 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care
format	neat
SMILES string	CC1=C(O)C(=O)C=CO1
InChI	1S/C6H6O3/c1-4-6(8)5(7)2-3-9-4/h2-3,8H,1H3
InChI key	XPCTZQVDEJYUGT-UHFFFAOYSA-N

Safety Information

pictograms	GHS07
signalword	Warning
hcodes	H302
pcodes	P264 - P270 - P301 + P312 - P501
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

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Mannitol

Empirical Formula (Hill Notation):	C₆H₁₄O₆
CAS Number:	69-65-8
Molecular Weight:	182.17
Beilstein/REAXYS Number:	1721898
EC Number:	200-711-8
MDL number:	MFCD00064287
PubChem Substance ID:	329823038
E Number:	E421
NACRES:	NA.24

Mannitol is an osmotic diuretic with a variety of clinical applications, one of which is the reduction of intracranial pressure. It is also found to be protective against ischemic and nephrotoxic acute renal failure.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Biochem/physiol Actions

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7668 in the slot below. This is an example certificate only and may not be the lot that you receive.

Параметры

Quality Level	300
grade	certified reference material, pharmaceutical secondary standard
form	neat
CofA	current certificate can be downloaded
analyte chemical class(es)	oligosaccharides
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	167-170 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule)
format	neat
pharmacopeia traceability	traceable to PhEur M0200000, traceable to USP 1375105
SMILES string	OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI	1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChI key	FBPFZTCFMRRESA-KVTDHHQDSA-N

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2

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meso-Erythritol

Empirical Formula (Hill Notation):	C₄H₁₀O₄
Linear Formula:	HOCH₂[CH(OH)]₂CH₂OH
CAS Number:	149-32-6
Molecular Weight:	122.12
Beilstein/REAXYS Number:	1719753
EC Number:	205-737-3
MDL number:	MFCD00004710
PubChem Substance ID:	329764644
NACRES:	NA.24

meso-Erythritol, belonging to the class of sugar alcohols, is identified in a variety of food products, fruits, vegetables, beverages and dietary supplements. It is known as a low glycemic food additive and plays an important role as a sweetener for diabetic patients, since it does not have glycemic or insulinemic effect due to its ability to not get metabolized but get absorbed in the small intestine. It is also reportedly used as a sugar substitute in toothpaste, chewing gums, confectionery food products, etc.

Application

meso-Erythritol may be used as an analytical reference standard for the quantification of the analyte in:

Food products using high-pressure liquid chromatography coupled to charged aerosol detector (HPLC-CAD).
Confectioneries using high-performance liquid chromatography with UV detection (HPLC-UV).
Food and beverages using liquid chromatography with UV detection (LC-UV).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Allelic variation of the Tas1r3 gene affects behavioral taste responses to this sugar alcohol, suggesting that it is a T1R3 receptor ligand.

Параметры

Quality Level	100
grade	analytical standard
assay	99.0% (GC)
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
impurities	1.0% water
bp	329-331 °C (lit.)
mp	118-120 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Flavors and Fragrances Food and Beverages Personal Care
format	neat
storage temp.	20°C
SMILES string	OC[C@@H](O)[C@@H](O)CO
InChI	1S/C4H10O4/c5-1-3(7)4(8)2-6/h3-8H,1-2H2/t3-,4+
InChI key	UNXHWFMMPAWVPI-ZXZARUISSA-N

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Methyl Paraben 47889

Empirical Formula (Hill Notation):	C₈H₈O₃
Linear Formula:	HOC₆H₄CO₂CH₃
CAS Number:	99-76-3
Molecular Weight:	152.15
Beilstein/REAXYS Number:	509801
EC Number:	202-785-7
MDL number:	MFCD00002352
PubChem Substance ID:	24871585
E Number:	E218

General description

Methyl paraben is basically a methyl ester of p-hydroxybenzoic acid. It is non-toxic, and non-carcinogenic in nature. It is a stable, non-volatile compound and finds application as an anti-microbial preservative in foods, drugs and cosmetics. It is readily absorbed through the skin and gastrointestinal tract. Upon hydrolyzation, it is hydrolyzed to p-hydroxybenzoic acid, and the conjugates formed get rapidly excreted in the urine.
Methyl Paraben is a stable, non-volatile, methyl ester of p-hydroxybenzoic acid. It can find applications as a broad-spectrum antimicrobial preservative in foods, drugs and cosmetics. It is found to be noncarcinogenic and is highly effective against fungi like molds and yeast as well as bacteria.

Application

Methyl paraben was used a preservative standard in commercial food products, during an experimental investigation, done to study the application of microemulsion electrokinetic chromatography (MEEKC), in detecting food preservatives.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Sigma-Aldrich International GmbH

Параметры

Quality Level	100
grade	analytical standard
product line	PESTANAL^®
form	neat
CofA	current certificate can be downloaded
packaging	ampule of 1000 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	125-128 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	room temp
SMILES string	COC(=O)c1ccc(O)cc1
InChI	1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
InChI key	LXCFILQKKLGQFO-UHFFFAOYSA-N
Gene Information	rat ... Ar(24208)

Safety Information

Pictograms	GHS09
Hazard Statements	H411
Precautionary Statements	P273 - P391 - P501
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	334.4 °F
Flash Point(C)	168 °C

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Natamycin

Empirical Formula (Hill Notation):	C₃₃H₄₇NO₁₃
CAS Number:	7681-93-8
Molecular Weight:	665.73
EC Number:	231-683-5
MDL number:	MFCD00135085
PubChem Substance ID:	329754196
E Number:	E235
NACRES:	NA.24

Natamycin is a polyene antibiotic that generally finds application as an antifungal agent as it lacks development of resistance and has a broad spectrum of activity. However, its mode of action is yet unclear, direct binding and isothermal titration calorimetry studies has revealed that natamycin binds specifically to ergosterol present in model membranes.
Natamycin shows activity against both molds and yeasts. It finds applications as a fungicidal and antibiotic preservative in the food industry.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Natamycin may be used as an analytical reference standard for the quantification of the analyte in wine samples using high-performance liquid chromatography coupled to electrospray ionization in positive mode high resolution mass spectrometry (HPLC-ESI-HR-MS) and reversed-phase high-performance liquid chromatography-tandem mass spectrometry technique (UHPLC-MS/MS).

Biochem/physiol Actions

An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane

Legal Information

VETRANAL is a registered trademark of Sigma-Aldrich Chemie GmbH

Параметры

Quality Level	100
grade	analytical standard
product line	VETRANAL^®
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	2-8°C
SMILES string	C[C@@H]1C\C=C\C=C\C=C\C=C\[C@@H](C[C@@H]2O[C@](O)(C[C@@H](O)C[C@H]3O[C@@H]3\C=C\C(=O)O1)C[C@H](O)[C@H]2C(O)=O)O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O
InChI	1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32+,33-/m1/s1
InChI key	NCXMLFZGDNKEPB-FFPOYIOWSA-N

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

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Neotame

Empirical Formula (Hill Notation):	C₂₀H₃₀N₂O₅
CAS Number:	165450-17-9
Molecular Weight:	378.46
Beilstein/REAXYS Number:	8352678
MDL number:	MFCD09039056
PubChem Substance ID:	329757524
E Number:	E961
NACRES:	NA.24

Neotame is chemically related to aspartame, an artificial sweetener, used in the production of sugar-free low-calorie foodstuffs. It is approved as a food additive depending upon the food or beverage application.
Neotame is a white colored, dipeptide methyl ester, which is found to be a highly potent and non-nutritive sweetener or flavour enhancer and hence finds applications in variety of foods. It is manufactured from aspartame and 3,3-dimethylbutyraldehyde in a one-step chemical synthesis process.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Neotame may be used as an analytical reference standard for the quantification of the analyte in the following:

Wine samples using reversed-phase high-performance liquid chromatography (RP-HPLC).
Wastewaters using hydrophilic interaction liquid chromatography (HILIC).
Food samples using high-performance liquid chromatography (HPLC).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Параметры

Quality Level	100
grade	analytical standard
assay	98.0% (HPLC)
form	neat
optical activity	[]/D -41.0±3.0°, c = 0.5 in H₂O
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NCCC(C)(C)C
InChI	1S/C20H30N2O5/c1-20(2,3)10-11-21-15(13-17(23)24)18(25)22-16(19(26)27-4)12-14-8-6-5-7-9-14/h5-9,15-16,21H,10-13H2,1-4H3,(H,22,25)(H,23,24)/t15-,16-/m0/s1
InChI key	HLIAVLHNDJUHFG-HOTGVXAUSA-N

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Octyl gallate

Empirical Formula (Hill Notation):	C₁₅H₂₂O₅
Linear Formula:	3,4,5-(HO)₃C₆H₂CO₂(CH₂)₇CH₃
CAS Number:	1034-01-1
Molecular Weight:	282.33
Beilstein/REAXYS Number:	2132305
EC Number:	213-853-0
MDL number:	MFCD00002197
PubChem Substance ID:	329748265
E Number:	E311
NACRES:	NA.24

Octyl gallate is an ester of gallic acid which is generally used as an antioxidant in food and pharmaceutical industries. It can act against the oxidative damage caused by reactive oxygen species (ROS) in the form of hydroxyl radicals or hydrogen peroxides, and reactive sulfur species (RSS)

Application

Octyl gallate may be used as a reference standard for the determination of octyl gallate in

edible vegetable oil by high performance liquid chromatography/time-of-flight mass spectrometry (HPLC/TOF-MS) as well as alternating penalty trilinear decomposition (APTLD) combined with HPLC-diode array detection (DAD)
dry foods by reversed-phase HPLC with photodiode array (PDA) detection.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Параметры

Quality Level	100
grade	analytical standard
assay	99.0% (HPLC)
shelf life	limited shelf life, expiry date on the label
mp	101-104 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	CCCCCCCCOC(=O)c1cc(O)c(O)c(O)c1
InChI	1S/C15H22O5/c1-2-3-4-5-6-7-8-20-15(19)11-9-12(16)14(18)13(17)10-11/h9-10,16-18H,2-8H2,1H3
InChI key	NRPKURNSADTHLJ-UHFFFAOYSA-N

Safety Information

pictograms	GHS07
signalword	Warning
hcodes	H302 - H317
pcodes	P280 - P301 + P312 + P330 - P302 + P352
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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Ponceau 4R

Empirical Formula (Hill Notation):	C₂₀H₁₁N₂Na₃O₁₀S₃
CAS Number:	2611-82-7
Molecular Weight:	604.47
Colour Index Number:	16255
Beilstein/REAXYS Number:	4122340
EC Number:	220-036-2
MDL number:	MFCD00004084
PubChem Substance ID:	329751631
E Number:	E124

Ponceau 4R is a synthetic red azo dye and is used as a food colorant. It is used in range of alcoholic and non-alcoholic beverages, food stuffs, preserved fruits etc. It exists as trisodium-2-hydroxy-1-(4-sulfonato-1-naphthylazo)-6,8-naphthalenedisulfonate.

Application

Ponceau 4R was used in the determination of contents of several additives in different non-alcoholic beverages using HPLC. It was used in understanding the genotoxicity of colorants. It was also used in preparing a falsified drink in the analysis of methanol-ethanol mixture using biosensors amperometric system.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Параметры

grade	analytical standard
Quality Level	100
assay	99.0% (HPLC)
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	[Na+].[Na+].[Na+].Oc1ccc2cc(cc(c2c1\N=N\c3ccc(c4ccccc34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O
InChI	1S/C20H14N2O10S3.3Na/c23-16-7-5-11-9-12(33(24,25)26)10-18(35(30,31)32)19(11)20(16)22-21-15-6-8-17(34(27,28)29)14-4-2-1-3-13(14)15;;;/h1-10,23H,(H,24,25,26)(H,27,28,29)(H,30,31,32);;;/q;3*+1/p-3/b22-21+;;;
InChI key	SWGJCIMEBVHMTA-ZRUFZDNISA-K

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Potassium disulfite

Empirical Formula (Hill Notation):	K₂O₅S₂
Linear Formula:	K₂S₂O₅
CAS Number:	16731-55-8
Molecular Weight:	222.32
EC Number:	240-795-3
MDL number:	MFCD00167605
PubChem Substance ID:	329758155
NACRES:	NA.24

Potassium disulfite (Potassium metabisulfite, PMB) is an inorganic salt with antimicrobial properties. It is a sulfiting agent that prevents browning of foods.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
assay	98% (RT)
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
solubility	H₂O: 200 mg/mL, clear to very slightly hazy, colorless
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	[K+].[K+].[O-]S(=O)S([O-])(=O)=O
InChI	1S/2K.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2
InChI key	RWPGFSMJFRPDDP-UHFFFAOYSA-L

Safety Information

pictograms	GHS05,GHS07
signalword	Danger
hcodes	H318 - H335
pcodes	P261 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338 - P403 + P233
Target Organs	Respiratory system
Supp Hazards	EUH031
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

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Potassium Sorbate 47848

Empirical Formula (Hill Notation):	C₆H₇KO₂
CAS Number:	24634-61-5
Molecular Weight:	150.22
EC Number:	246-376-1
MDL number:	MFCD00016546
PubChem Substance ID:	24871514
E Number:	E202

General description

Potassium sorbate is a food additive, used for the prevention of food spoilage originating from bacteria, molds or yeasts. It exists in a variety of products such as pharmaceuticals, cosmetics and employed for preserving processed foods including fruit juices, soda, soy sauce, ketchup, etc.
Potassium sorbate is a preservative, commonly used in a variety of food and beverages. It is a food antimicrobial agent, which can act effectively along a wide pH range to inhibit the growth of yeast, molds and some bacteria.

Application

Potassium sorbate may be used as an analytical reference standard for the quantification of the analyte in food, beverages and soft drinks using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
form	neat
CofA	current certificate can be downloaded
packaging	ampule of 1000 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
antibiotic activity spectrum	fungi
format	neat
storage temp.	room temp
SMILES string	[K+].C\C=C\C=C\C([O-])=O
InChI	1S/C6H8O2.K/c1-2-3-4-5-6(7)8;/h2-5H,1H3,(H,7,8);/q;+1/p-1/b3-2+,5-4+;
InChI key	CHHHXKFHOYLYRE-STWYSWDKSA-M

Safety Information

pictograms	GHS07
signalword	Warning
hcodes	H319
pcodes	P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1

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Pullulan Standard Set Mp ~350 - 700000 96351-1KT

CAS Number:	9057-02-7
EC Number:	232-945-1
E Number:	E1204
NACRES:	NA.24

General description

Pullulan Standards are mostly used to obtain molecular mass distribution of cellulosic samples. It mainly consists of polymaltotriose units linked together by α-(1→6) linkages.

Application

Pullulan standard set may be used as a calibration standard for the quantitative analysis of membrane formation process of alginate–chitosan microcapsules using gel permeation chromatography(GPC).

Components

Kit with carefully selected reference materials to calibrate GPC/SEC/GFC systems. The kit contains standards of the same type, but with different molar masses, a certificate of analysis (CoA) for each standard and an example calibration curve with analytical conditions.
The standards need to be weighed before use. Suitable for calibrations in aqueous solutions and DMSO.
Kit contains 10 different pullulan standards, each 100 mg, with Mp ranging from ~350 to ~700,000.

Параметры

grade	analytical standard, for GPC
Quality Level	100
form	neat
shelf life	limited shelf life, expiry date on the label
analyte chemical class(es)	oligosaccharides
application(s)	gel permeation chromatography (GPC): suitable
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	2-8°C

Safety Information

Personal Protective Equipment	Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point F	Not applicable
Flash Point C	Not applicable

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Riboflavin (B2) 47861

Empirical Formula (Hill Notation):	C₁₇H₂₀N₄O₆
CAS Number:	83-88-5
Molecular Weight:	376.36
Beilstein/REAXYS Number:	97825
EC Number:	201-507-1
MDL number:	MFCD00005022
PubChem Substance ID:	24871529
E Number:	E101

General description

Riboflavin (B2) is a vitamin, which is a vital component of mitochondrial energy production. It can be used in the treatment of mitochondrial dysfunction and also for the prophylactic treatment of migraine in adults. It is a part of the coenzyme flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), involved in a number of oxidation and reduction reactions.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Riboflavin (B2) may be used as an analytical reference standard for the quantification of the analyte in neutraceutical products and food products using high-performance liquid chromatography technique.

Параметры

Quality Level	100
grade	analytical standard
form	neat, solid
CofA	current certificate can be downloaded
feature	standard type water soluble vitamin
packaging	ampule of 1000 mg
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	290 °C (dec.) (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care Pharmaceutical (small molecule) Vitamins, Nutraceuticals, and Natural Products
format	neat
storage temp.	room temp
SMILES string	CC1=C(C)C=C(N(C[C@H](O)[C@@H]([C@H](O)CO)O)C(C2=N3)=NC(NC2=O)=O)C3=C1
InChI	1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1
InChI key	AUNGANRZJHBGPY-SCRDCRAPSA-N

Safety Information

Personal Protective Equipment	Eyeshields, Gloves, type N95 (US)
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

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Sodium Cyclamate 47827

Empirical Formula (Hill Notation):	C₆H₁₂NNaO₃S
Linear Formula:	C₆H₁₁NHSO₃Na
CAS Number:	139-05-9
Molecular Weight:	201.22
Beilstein/REAXYS Number:	4166868
EC Number:	205-348-9
MDL number:	MFCD00003827
PubChem Substance ID:	24871485
E Number:	E952

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sodium cyclamate may be used as a reference standard in the determination of sodium cyclamate in artificial food and beverages using ion chromatography (IC).

Biochem/physiol Actions

Phenylsulfamate sweet tastant detectable by humans. ′First generation′ sweetener studied in animal models for its carcinogenic potential.

Параметры

Quality Level	100
grade	analytical standard
form	neat
CofA	current certificate can be downloaded
packaging	pkg of 1 g
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	>300 °C (lit.)
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
storage temp.	room temp
SMILES string	[Na+].[O-]S(=O)(=O)NC1CCCCC1
InChI	1S/C6H13NO3S.Na/c8-11(9,10)7-6-4-2-1-3-5-6;/h6-7H,1-5H2,(H,8,9,10);/q;+1/p-1
InChI key	UDIPTWFVPPPURJ-UHFFFAOYSA-M

Safety Information

Personal Protective Equipment	dust mask type N95 (US), Eyeshields, Gloves
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point F	Not applicable
Flash Point C	Not applicable

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Sodium formate

Empirical Formula (Hill Notation):	CHNaO₂
Linear Formula:	HCOONa
CAS Number:	141-53-7
Molecular Weight:	68.01
Beilstein/REAXYS Number:	3595134
EC Number:	205-488-0
MDL number:	MFCD00013101
PubChem Substance ID:	329760478

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Параметры

Quality Level	100
grade	analytical standard
assay	99.0-101.0 wt. % (NT)
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
pH	7.0-8.5
mp	259-262 °C (lit.)
solubility	H₂O: 10%, clear, colorless
UV absorption	: 260 nm A_max: 0.05, : 270 nm A_max: 0.04, : 300 nm A_max: 0.03, : 330 nm A_max: 0.02, : 500 nm A_max: 0.02
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	[Na+].[O-]C=O
InChI	1S/CH2O2.Na/c2-1-3;/h1H,(H,2,3);/q;+1/p-1
InChI key	HLBBKKJFGFRGMU-UHFFFAOYSA-M

Safety Information

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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Sodium metabisulfite

Empirical Formula (Hill Notation):	Na₂O₅S₂
Linear Formula:	Na₂S₂O₅
CAS Number:	7681-57-4
Molecular Weight:	190.11
EC Number:	231-673-0
MDL number:	MFCD00167602
PubChem Substance ID:	329748655
E Number:	E223
NACRES:	NA.24

Sodium metabisulfite is primarily used as an antioxidant and antimicrobial agent in a wide variety of foods and drugs. It is also used as the main additive in the prevention of melanosis in shrimp.

Application

Sodium metabisulfite may be used as an antioxidant which when added to anesthetic formulations serves to minimize epinephrine oxidation in the quantification of epinephrine in dental anesthetic solutions by capillary electrophoresis. Sodium metabisulfite may also be used as a standard in the determination of catecholamines in human plasma by high-performance liquid chromatography with electrochemical detection.

Analysis Note

metal trace analysis: corresponds to requirements

Параметры

Quality Level	100
grade	analytical standard
assay	98.0% (iodometric, RT)
shelf life	limited shelf life, expiry date on the label
mp	>300 °C (lit.)
anion traces	chloride (Cl^-): 50 mg/kg, thiosulfate (S₂O₃^2-): 500 mg/kg
cation traces	As: 0.5 mg/kg, Ca: 10 mg/kg, Cd: 5 mg/kg, Co: 5 mg/kg, Cr: 5 mg/kg, Cu: 5 mg/kg, Fe: 5 mg/kg, K: 200 mg/kg, Mg: 5 mg/kg, Mn: 5 mg/kg, Ni: 5 mg/kg, Pb: 5 mg/kg, Zn: 5 mg/kg
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	[Na+].[Na+].[O-]S(=O)S([O-])(=O)=O
InChI	1S/2Na.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2
InChI key	HRZFUMHJMZEROT-UHFFFAOYSA-L

Safety Information

pictograms	GHS05,GHS07
signalword	Danger
hcodes	H302 - H318
pcodes	P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P501
Supp Hazards	EUH031
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point F	Not applicable
Flash Point C	Not applicable

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Sodium nitrate

Empirical Formula (Hill Notation):	NNaO₃
Linear Formula:	NaNO₃
CAS Number:	7631-99-4
Molecular Weight:	84.99
EC Number:	231-554-3
MDL number:	MFCD00011119
PubChem Substance ID:	329750988
NACRES:	NA.24

Sodium nitrate is a nitrate salt of sodium, which finds application as a preservative in cured meat products for the protection against Clostridium botulinum and other Clostridium species.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sodium nitrate may be used as an analytical reference standard for the quantification of the analyte in the following:

Ham using reversed-phase high-performance liquid chromatography with diode array detection (RP-HPLC-DAD).
Human saliva samples using ion chromatography (IC) technique.

Параметры

Quality Level	100
grade	analytical standard
assay	99.995% trace metals basis
form	neat
shelf life	limited shelf life, expiry date on the label
application(s)	HPLC: suitable, gas chromatography (GC): suitable
mp	306 °C (dec.) (lit.)
solubility	water: soluble 874 g/L at 20 °C
cation traces	B: 1 mg/kg
suitability	conforms to structure for Infrared spectrum
Featured Industry	Cleaning Products Cosmetics Food and Beverages Personal Care
format	neat
SMILES string	[Na+].[O-][N+]([O-])=O
InChI	1S/NO3.Na/c2-1(3)4;/q-1;+1
InChI key	VWDWKYIASSYTQR-UHFFFAOYSA-N

Safety Information

pictograms	GHS03,GHS07
signalword	Warning
hcodes	H272 - H319
pcodes	P210 - P305 + P351 + P338
RIDADR	UN 1498 5.1 / PGIII
WGK Germany	WGK 1
Flash Point F	does not flash
Flash Point C	does not flash

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Оборудование хранится на сухом отапливаемом складе, где поддерживается ровная температура.

Доставим по Москве на следующий день, по России — за 3-4 дня

Работаем с PonyExpress и Деловыми линиями. Вы также можете выбрать свою транспортную компанию или забрать товар со склада в Москве.

Выполним бесплатный ремонт и сервисное обслуживание

В случае любых неполадок за свой счет выполним ремонт в сервисном центре или на заводе-изготовителе. Или бесплатно заменим прибор на новый.

Обеспечим легкое внедрение на предприятие

Производим пуско-наладку оборудования, валидацию, обучение сотрудников. Если нужно, привлекаем инженеров с заводов- изготовителей.

Отзывы

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Назначение стандартов пищевых добавок

Референсные материалы используются для построения калибровочных кривых, подтверждения подлинности пиков на хроматограммах и контроля правильности измерений. Они помогают точно определять содержание консервантов, красителей, подсластителей, антиоксидантов и других добавок даже при низких концентрациях и в сложных пищевых матрицах.

Основные типы стандартов

Индивидуальные стандарты соединений

Чистые вещества применяются для точной идентификации и количественного анализа конкретных добавок при разработке и валидации методик.

Многокомпонентные стандартные смеси

Позволяют одновременно калибровать систему по нескольким соединениям, что повышает эффективность лабораторий с большим потоком проб.

Внутренние стандарты

Используются для компенсации потерь вещества и матричных эффектов на этапах пробоподготовки и анализа, обеспечивая более точные результаты количественных измерений.

Материалы для контроля качества

Применяются в рутинной работе лабораторий для регулярной проверки стабильности аналитических систем и подтверждения воспроизводимости результатов.

Ключевые критерии выбора

Соответствие аналитической задаче

Важно учитывать перечень определяемых добавок, тип пищевой матрицы и используемый метод анализа — ВЭЖХ, ГХ, спектрофотометрия или титриметрия.

Диапазон концентраций

Концентрации стандартов должны перекрывать рабочий диапазон методики, чтобы обеспечить корректное построение калибровочных зависимостей.

Степень чистоты и документация

Высокая химическая чистота и наличие сопроводительной документации необходимы для достоверных результатов и прохождения аудитов систем качества.

Форма поставки и стабильность

Растворы или сухие формы выбираются с учётом условий хранения, срока годности и удобства применения в лабораторной практике.

Сферы применения

производственные лаборатории пищевых предприятий;
независимые испытательные и аккредитованные лаборатории;
контроль безопасности и соответствия нормативным требованиям;
разработка и валидация аналитических методик;
научно-исследовательские проекты в области пищевой химии;
межлабораторные сравнительные испытания.

Преимущества для B2B-заказчиков

Применение стандартов пищевых добавок снижает аналитические риски, упрощает процедуры валидации и обеспечивает соответствие требованиям технических регламентов и систем менеджмента качества. Для предприятий это означает стабильность контроля, уверенность в достоверности данных и готовность к проверкам со стороны регуляторов и партнёров.

Каталог

Food Additive Standards

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С 2010 года мы поставляем оборудование с заводов Европы. Берем на себя все — от подбора оборудования до внедрения на предприятии

Отзывы

В числе наших клиентов организации из разных отраслей

Назначение стандартов пищевых добавок

Основные типы стандартов

Индивидуальные стандарты соединений

Многокомпонентные стандартные смеси

Внутренние стандарты

Материалы для контроля качества

Ключевые критерии выбора

Соответствие аналитической задаче

Диапазон концентраций

Степень чистоты и документация

Форма поставки и стабильность

Сферы применения

Преимущества для B2B-заказчиков

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