cis-5,8,11,14,17-Eicosapentaenoic acid
Empirical Formula (Hill Notation): | C20H30O2 |
Linear Formula: | CH3(CH2CH=CH)5(CH2)3CO2H |
CAS Number: | 10417-94-4 |
Molecular Weight: | 302.45 |
Beilstein/REAXYS Number: | 1714433 |
MDL number: | MFCD00065716 |
PubChem Substance ID: | 24894450 |
NACRES: | NA.77 |
Кат. номер |
E2011-10MG |
E2011-100MG |
E2011-50MG |
E2011-25MG |
E2011-5MG |
Eicosapentaenoic acid is a polyunsaturated fatty acid (PUFAs) and is synthesized from linolenic acid. It is distributed in phospholipid bilayers of the cell membrane, synaptic membranes of the brain and retina. It is obtained majorly from fish oil, seaweed, phytoplankton, and camelina. Being an Omega-3 fatty acid, it shows cis-trans conformations.
cis-5,8,11,14,17-Eicosapentaenoic acid has been used:
- to test pharmacologic effect on steatosis in hepatocytes
- as an analytical standard in Raman spectra measurements to characterize human breast cancer samples
- in lipid peroxidation assay in mouse embryonic fibroblasts and in pre-treatment of cells for cell viability studies
10, 25, 50, 100 mg in ampule
Eicosapentaenoic acid (EPA) is essential for healthy living and alleviates obesity. It decreases the triglyceride levels by modulating very-low-density lipoprotein(VLDL) levels.
5-Lipoxygenase inhibitor; reduces thromboxane A2 production.
biological source | fish oil |
Quality Level | 200, |
assay | 99% |
form | liquid |
refractive index | n20/D 1.4977 (lit.) |
mp | 54-53 °C (lit.) |
solubility | methanol: 50 mg/mL, clear, colorless |
density | 0.943 g/mL at 25 °C (lit.) |
storage temp. | 20°C |
SMILES string | CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O |
InChI | 1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15- |
InChI key | JAZBEHYOTPTENJ-JLNKQSITSA-N |
Gene Information | human ... ALOX5(240) mouse ... ALOX5(11689), Pparg(19016) rat ... ALOX5(25290) |
Personal Protective Equipment | Faceshields,, Gloves,, Goggles,, type ABEK (EN14387) respirator filter, |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point F | 200.1 °F - closed cup |
Flash Point C | 93.4 °C - closed cup |