WR304 mAb 330021S-100UG

NACRES:

NA.41

WR304 is an antibody that binds specifically to the lipids PIP and PIP2. WR304 also neutralizes infectious HIV-1 virus and can be used to probe the presence of PIP and PIP2 in membranes in a variety of applications including inositol phosphate-dependent cell signaling pathways. This antibody was developed by the Walter Reed Army Institute of Research (WRAIR) using a targeted adjuvant protocol with liposomes containing Avantis Lipid A.
Formulation: WR304 is provided as a 0.2µm sterile-filtered solution in Tris buffered saline (TBS). WR304 binding to porcine brain PI(4)P is inhibited by high concentration of Ca2+ (10 mM)iv and addition of 1 mM EDTA stimulates this binding activity. PBS and other phosphate-containing buffers should not be used as they inhibit binding to the phospholipid head groupiii.
WR304 recognizes PIP and PIP2, and neutralizes HIV-1 virus.
Antigens: Brain PI(4)P
ELISA, IHC, Dot Blot, Flow cytometry and HIV-1 infectivity.
The WR304 antibody has been used for the quantitation of PIP/PIP2 in direct ELISA and Dot Blot analysis. The WR304 antibody specifically binds to PIP/PIP2 and inhibits the infectivity of HIV-1 to peripheral blood mononuclear cells (PBMC).
0.5 mL Polypropylene Tube with Screw Cap (330021S-100ug)
Store undiluted at either -20°C or -80°C.
Hazardous/Non-hazardous Components: This product contains no substances that, at their given concentration, are known to be hazardous to health. Therefore, there is no MSDS for this product.
Ig Class: Mouse IgM (kappa).
Antibody Source: Monoclonal antibody from BALB/c-derived hybridoma WR304.
Production: In vitro cell culture. Purification: Ultra filtration through 100 KDa cut-off filters.
Purification: Ultra filtration through 100 KDa cut-off filters.

antibody form	purified immunoglobulin
antibody product type	primary antibodies
assay	>95%
packaging	pkg of 1 x 0.1 mL (polypropylene tube with screw cap (330021S-100ug))
Торговая марка	Avanti Polar Lipids
concentration	1 mg/mL (330021S-100ug)
shipped in	dry ice
storage temp.	−70°C

RIDADR	NONH for all modes of transport
WGK Germany	nwg
Flash Point F	Not applicable
Flash Point C	Not applicable